MED16

Mediator of RNA polymerase II transcription subunit 16 · Q9Y2X0 · MED16 on Sugi Atlas →

0 patent compounds predicted against MED16, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MED16 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt PHASE4COMPLETED
Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome PHASE3UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Spironolactone and XPB-1 Integrity in the TFIIH Complex nanENROLLING_BY_INVITATION
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults nanCOMPLETED
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
miR-155 Expression in Episodic and Chronic Migraine nanUNKNOWN
The Molecular Pathogenesis Study of Cataract nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
PCM1-JAK2 in Therapy Related Neoplasms nanUNKNOWN
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells. nanUNKNOWN
Role of Piwi-protein Interacting RNA, miRNA-194 and Amino Acids in Patients With Prostate Cancer nanUNKNOWN
The Difference of microRNA and Circulating Tumor Cells in Blood Among Cancer Patients With Immunotherapy nanRECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Search for Bovine miRNA Transference to Humans nanCOMPLETED
Methylation of DNA in Children and Adolescents With Type 1 Diabetes Mellitus (METHYLDIAB) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MED16 binder may also engage these)

ProteinNameSimilarity
Q6PGF3 1.000 Q6PGF3 →
Q566H4 1.000 Q566H4 →
Q8WYP5 0.994 Q8WYP5 →
Q9H2M9 0.993 Q9H2M9 →
B1WC10 0.993 B1WC10 →
Q08D69 0.992 Q08D69 →
O95876 0.992 O95876 →
O88480 0.991 O88480 →
A2A9C3 0.991 A2A9C3 →
Q8CEC0 0.990 Q8CEC0 →
Q8C0M0 0.990 Q8C0M0 →
Q9C0B7 0.990 Q9C0B7 →
A7UA95 0.989 A7UA95 →
Q80U93 0.989 Q80U93 →
Q9QY53 0.989 Q9QY53 →
Q8C3S2 0.989 Q8C3S2 →
O75800 0.989 O75800 →
Q15061 0.989 Q15061 →
Q8BMG7 0.989 Q8BMG7 →
Q99K74 0.988 Q99K74 →
A2CEI4 0.988 A2CEI4 →
Q5U1Z0 0.988 Q5U1Z0 →
Q99ML0 0.988 Q99ML0 →
F1QEB7 0.987 F1QEB7 →
Q62141 0.987 Q62141 →
Q8K1X1 0.987 Q8K1X1 →
Q5ZLG9 0.987 Q5ZLG9 →
Q16K67 0.987 Q16K67 →
PIK3C2B Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 0.987 landscape →
Q6PFH3 0.987 Q6PFH3 →