MET
Hepatocyte growth factor receptor · P08581 · MET on Sugi Atlas →
272,574 patent compounds predicted against MET, 173,834 high-confidence (nearest known ligand ≥ 0.5)
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours | |
|---|---|---|---|
| Mk-2461 (SCHEMBL93526) | 1.00 | 20/20 | |
| Pf-04217903 (SCHEMBL93550) | 1.00 | 20/20 | |
| SCHEMBL104141 | 0.82 | 20/20 | |
| SCHEMBL105700 | 0.82 | 20/20 | |
| SCHEMBL104578 | 0.77 | 20/20 | |
| SCHEMBL105701 | 0.75 | 20/20 | |
| SCHEMBL106402 | 0.74 | 20/20 | |
| SCHEMBL106456 | 0.72 | 20/20 | |
| SCHEMBL105699 | 0.71 | 20/20 | |
| SCHEMBL105698 | 0.70 | 20/20 | |
| SCHEMBL106728 | 0.70 | 20/20 | |
| SCHEMBL108517 | 0.70 | 20/20 | |
| SCHEMBL104160 | 0.69 | 20/20 | |
| Glesatinib (SCHEMBL106319) | 1.00 | 19/20 | |
| SCHEMBL141721 | 0.81 | 19/20 | |
| SCHEMBL104760 | 0.78 | 19/20 | |
| SCHEMBL139114 | 0.74 | 19/20 | |
| SCHEMBL106729 | 0.73 | 19/20 | |
| SCHEMBL106325 | 0.69 | 19/20 | |
| SCHEMBL141854 | 0.67 | 19/20 |
Clinical trials — most relevant to MET by text similarity (a relevance ranking, not an exhaustive list)
Related proteins — ESM-2 sequence neighbours (a MET binder may also engage these)
| Protein | Name | Similarity | |
|---|---|---|---|
| A0M8R7 | — | 1.000 | A0M8R7 → |
| Q09YH7 | — | 1.000 | Q09YH7 → |
| Q07DZ1 | — | 1.000 | Q07DZ1 → |
| Q09YN5 | — | 1.000 | Q09YN5 → |
| Q75ZY9 | — | 1.000 | Q75ZY9 → |
| Q769I5 | — | 1.000 | Q769I5 → |
| Q2QLA9 | — | 1.000 | Q2QLA9 → |
| Q09YK0 | — | 1.000 | Q09YK0 → |
| Q108U6 | — | 1.000 | Q108U6 → |
| Q00PJ8 | — | 1.000 | Q00PJ8 → |
| Q2QLH6 | — | 1.000 | Q2QLH6 → |
| Q07E01 | — | 1.000 | Q07E01 → |
| Q2IBD8 | — | 1.000 | Q2IBD8 → |
| Q2QLF1 | — | 1.000 | Q2QLF1 → |
| Q2IBF2 | — | 1.000 | Q2IBF2 → |
| Q2QLC0 | — | 1.000 | Q2QLC0 → |
| Q2QLG5 | — | 1.000 | Q2QLG5 → |
| A1X150 | — | 1.000 | A1X150 → |
| Q2IBA6 | — | 1.000 | Q2IBA6 → |
| Q07E37 | — | 1.000 | Q07E37 → |
| Q2IBC0 | — | 1.000 | Q2IBC0 → |
| Q09YI9 | — | 1.000 | Q09YI9 → |
| P97523 | — | 1.000 | P97523 → |
| Q07DY1 | — | 1.000 | Q07DY1 → |
| Q07DV8 | — | 1.000 | Q07DV8 → |
| P16056 | — | 1.000 | P16056 → |
| Q2IBG7 | — | 1.000 | Q2IBG7 → |
| Q2QLE0 | — | 1.000 | Q2QLE0 → |
| Q07E48 | — | 1.000 | Q07E48 → |
| Q07E24 | — | 1.000 | Q07E24 → |