MTDH

Protein LYRIC · Q86UE4 · MTDH on Sugi Atlas →

0 patent compounds predicted against MTDH, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MTDH by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
DTGM Fusion Protein in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia PHASE1/PHASE2COMPLETED
A Study of LY2157299 in Participants With Hepatocellular Carcinoma PHASE2COMPLETED
Safety and Efficacy of AEG33773 Versus Placebo in Patients With Painful Diabetic Peripheral Neuropathy PHASE2COMPLETED
Study of Weekly Carfilzomib, Cyclophosphamide and Dexamethasone In Newly Diagnosed Multiple Myeloma Patients (wCCyd) PHASE1/PHASE2COMPLETED
Vaccine Therapy in Treating Patients With Stage IV Melanoma PHASE2COMPLETED
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant PHASE1/PHASE2RECRUITING
Phase I/II Study of Carfilzomib, Pomalidomide and Dexamethasone in Relapsed And/Or Refractory Multiple Myeloma Patients (CPD) PHASE1/PHASE2COMPLETED
Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma PHASE1/PHASE2RECRUITING
Ramucirumab (Cyramza), Nal-IRI (ONIVYDE) and Trifluridine/Tipiracil (Lonsurf) in Second Line Metastatic Gastric Cancer . PHASE1/PHASE2RECRUITING
Filanesib (ARRY-520) in Combination With Pomalidomide and Dexamethasone for Relapsed/Refractory (R/R) Multiple Myeloma (MM) Patients PHASE1/PHASE2COMPLETED
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas PHASE1/PHASE2COMPLETED
The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs PHASE2RECRUITING
9-ING-41 in Patients With Advanced Cancers PHASE2ACTIVE_NOT_RECRUITING
A Phase 1 Study of SH1573 Capsules in Subjects With Refractory or Relapsed Acute Myelogenous Leukemia PHASE1UNKNOWN
Monoclonal Antibody F19 in Treating Patients With Advanced or Metastatic Cancer PHASE1COMPLETED
AEG35156 and Docetaxel in Treating Patients With Solid Tumors PHASE1COMPLETED
Fenretinide in Treating Patients With Refractory or Relapsed Hematologic Cancer PHASE1COMPLETED
AEG35156 and Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Solid Tumors PHASE1COMPLETED
A Study of Investigational Drug CFI-402257 in Patients With Advanced Solid Tumors PHASE1COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
PV701 in Treating Patients With Advanced or Recurrent Peritoneal Cancer PHASE1COMPLETED
Photodynamic Therapy With HPPH in Treating Patients With Non-Small Cell Lung Cancer PHASE1COMPLETED
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms PHASE1RECRUITING
Once or Twice Daily Administration of BIIB021 to Subjects With Advanced Solid Tumors PHASE1COMPLETED
Phase I Trial of LCL161 and Gemcitabine Plus Nab-Paclitaxel in Metastatic Pancreatic Cancer PHASE1UNKNOWN
Liposome Encapsulated SN38 (LE-SN38) in Patients With Advanced Cancer PHASE1COMPLETED
Phase Ib Study to Determine MTD of AZD1775 Monotherapy in Patients With Locally Advanced or Metastatic Solid Tumours. PHASE1COMPLETED
A Safety Study of Abiraterone Acetate Administered in Combination With Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC) PHASE1COMPLETED
Intensity Modulated Radiation Therapy for Prostate Cancer EARLY_PHASE1COMPLETED
Establishment of a Prospective Clinical-biological Database nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a MTDH binder may also engage these)

ProteinNameSimilarity
Q80WJ7 1.000 Q80WJ7 →
Q9Z1W6 1.000 Q9Z1W6 →
Q8N3X1 0.984 Q8N3X1 →
Q5REG6 0.983 Q5REG6 →
Q96T21 0.983 Q96T21 →
Q6PGL7 0.982 Q6PGL7 →
B0KYV5 0.982 B0KYV5 →
Q61029 0.982 Q61029 →
O75410 0.982 O75410 →
D3ZUI5 0.981 D3ZUI5 →
Q4KLH6 0.981 Q4KLH6 →
A4IGN8 0.980 A4IGN8 →
TMPO Lamina-associated polypeptide 2, isoforms beta/gamma 0.980 landscape →
Q6ZQ06 0.980 Q6ZQ06 →
Q6ZQ03 0.979 Q6ZQ03 →
Q61464 0.979 Q61464 →
Q05A80 0.979 Q05A80 →
O80386 0.979 O80386 →
Q9BTC0 0.979 Q9BTC0 →
Q96B01 0.979 Q96B01 →
Q62733 0.979 Q62733 →
P0DQW0 0.978 P0DQW0 →
Q6INC4 0.978 Q6INC4 →
O88573 0.978 O88573 →
MAP7 Ensconsin 0.978 landscape →
Q91Y25 0.978 Q91Y25 →
AFF1 AF4/FMR2 family member 1 0.978 landscape →
AFF4 AF4/FMR2 family member 4 0.978 landscape →
Q80X08 0.978 Q80X08 →
Q58CQ0 0.977 Q58CQ0 →