MUC1

Mucin-1 · P15941 · MUC1 on Sugi Atlas →

6 patent compounds predicted against MUC1, 6 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL24183778 SCHEMBL24183778 0.65 1/20
SCHEMBL19236007 SCHEMBL19236007 0.54 1/20
SCHEMBL23023220 SCHEMBL23023220 0.54 1/20
SCHEMBL29638011 SCHEMBL29638011 0.54 1/20
SCHEMBL29824440 SCHEMBL29824440 0.54 1/20
SCHEMBL21139390 SCHEMBL21139390 0.53 1/20

Clinical trials — most relevant to MUC1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Immunotherapy With TG4010 in Patients With Advanced Non-Small Cell Lung Cancer PHASE2/PHASE3COMPLETED
Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease PHASE1/PHASE2UNKNOWN
A Novel Vaccine for the Treatment of MUC1-expressing Tumor Malignancies PHASE2WITHDRAWN
A Controlled Study of the Effectiveness of Oregovomab (Antibody) Plus Chemotherapy in Advanced Ovarian Cancer PHASE2COMPLETED
L-BLP25 in Patients With Colorectal Carcinoma After Curative Resection of Hepatic Metastases PHASE2COMPLETED
Study of ZGGS34 in Participants With Advanced Solid Tumors PHASE1/PHASE2RECRUITING
PankoMab-GEX™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer PHASE2COMPLETED
OPT-821 With or Without Vaccine Therapy in Treating Patients With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer in Second or Third Complete Remission PHASE2COMPLETED
CAR T and PD-1 Knockout Engineered T Cells for Esophageal Cancer PHASE1/PHASE2UNKNOWN
Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps PHASE2ACTIVE_NOT_RECRUITING
PANVAC-V and PANVAC-F Vaccines Plus Sargramostim to Treat Advanced Cancer PHASE1/PHASE2COMPLETED
Study of Tecemotide (L-BLP25) in Subjects With Slowly Progressive Multiple Myeloma With no Symptoms and Who Have Had no Chemotherapy PHASE2COMPLETED
Vaccine Therapy in Treating Patients With Breast Cancer PHASE1COMPLETED
P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors PHASE1ACTIVE_NOT_RECRUITING
Anti-cancer MUC1-specific Immunotherapy for Unresectable Stage III Non-small Cell Lung Cancer PHASE1WITHDRAWN
MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer PHASE1RECRUITING
MUC1 Vaccine in Conjunction With Poly-ICLC in Patients With Recurrent and/or Advanced Prostate Cancer PHASE1COMPLETED
Vaccine Therapy in Treating Patients With Advanced Cancer PHASE1COMPLETED
Vaccine Therapy in Treating Patients With Ovarian, Fallopian Tube, or Peritoneal Cancer PHASE1COMPLETED
MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer PHASE1ACTIVE_NOT_RECRUITING
Vaccine Therapy Plus QS21 in Treating Patients With Prostate Cancer PHASE1COMPLETED
Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors PHASE1ACTIVE_NOT_RECRUITING
Vaccine Therapy in Treating Patients With Resected or Locally Advanced Unresectable Pancreatic Cancer PHASE1COMPLETED
Genetically Engineered Cells (MUC1-Activated T-Cells) for the Treatment of MUC1 Positive Recurrent or Refractory Multiple Myeloma PHASE1ACTIVE_NOT_RECRUITING
Phase 1 Study of ONT-10 in Patients With Solid Tumors PHASE1COMPLETED
MUC1 Vaccine for Triple-negative Breast Cancer EARLY_PHASE1COMPLETED
Vaccine Therapy in Treating Patients With Previously Treated Stage II or Stage III Breast Cancer EARLY_PHASE1COMPLETED
Investigating Mucinase Activity in Airway Disease nanCOMPLETED
Assessing Response to Neoadjuvant Chemotherapy With HD PET/CT, Serum Glycomic Markers and Tissue Muc-1 Isoforms nanCOMPLETED
Personalized Exercise Coaching to Improve Quality of Life in Pediatric IBD nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MUC1 binder may also engage these)

ProteinNameSimilarity
P0C727 0.963 P0C727 →
P0C728 0.963 P0C728 →
P12027 0.957 P12027 →
P13208 0.939 P13208 →
P24856 0.937 P24856 →
P21787 0.933 P21787 →
P0C732 0.932 P0C732 →
Q27905 0.930 Q27905 →
P13821 0.930 P13821 →
P08519 0.929 P08519 →
A6NJU9 0.928 A6NJU9 →
Q1HVI8 0.927 Q1HVI8 →
C9JG80 0.925 C9JG80 →
Q8AZK7 0.925 Q8AZK7 →
Q95JC9 0.921 Q95JC9 →
P0DPF2 0.921 P0DPF2 →
Q03650 0.921 Q03650 →
A8MRT5 0.916 A8MRT5 →
Q9NQZ3 0.916 Q9NQZ3 →
Q63429 0.914 Q63429 →
E5RHQ5 0.914 E5RHQ5 →
P0CG61 0.912 P0CG61 →
P0CG64 0.912 P0CG64 →
P62976 0.912 P62976 →
Q9URU4 0.911 Q9URU4 →
P0CG69 0.911 P0CG69 →
P0CG50 0.910 P0CG50 →
P08640 0.910 P08640 →
Q92617 0.910 Q92617 →
P03181 0.910 P03181 →