MYL4 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to MYL4 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem	PHASE2/PHASE3	COMPLETED
COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure	PHASE2	COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability	PHASE1	COMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill	nan	UNKNOWN
Genetic Analysis of African-Americans With High Blood Pressure	nan	COMPLETED
Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium	nan	COMPLETED
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies	nan	RECRUITING
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People	nan	COMPLETED
Chronic Muscle Disuse in the Elderly	nan	COMPLETED
Muscle Tissue Bank for Muscular Dystrophy	nan	COMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer	nan	UNKNOWN
Study of Genotype and Phenotype Characterization in Duchenne Muscular Dystrophy With Small Mutations	nan	UNKNOWN
Congenital Muscle Disease Study of Patient and Family Reported Medical Information	nan	RECRUITING
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia	nan	COMPLETED
3D-Microscopic Muscle Architecture in Cerebral Palsy	nan	RECRUITING
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms	nan	COMPLETED
Effect of Exercise on the Human Skeletal Muscle Phosphoproteome	nan	COMPLETED
A Multicenter Phenotype-Genotype Analysis of LGMD Patients in China	nan	ENROLLING_BY_INVITATION
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.	nan	RECRUITING
Characteristics of Nondystrophic Myotonias	nan	COMPLETED
Natural History Study for Patients With Nemaline Myopathy in Belgium	nan	NOT_YET_RECRUITING
Muscle Wasting in Cancer (MWIC)	nan	COMPLETED
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development	nan	COMPLETED
Molecular and Genetic Studies of Congenital Myopathies	nan	RECRUITING
Evaluating Changes in Skeletal Muscle Proteins Following Resistance Exercise and Single-Leg Disuse	nan	COMPLETED
Imaging Genetics of Laryngeal Dystonia	nan	RECRUITING
Signs and Symptoms Associated With Molecular Defects in Genetically Inherited Heart Disease	nan	COMPLETED
Pediatric Cardiomyopathy Mutation Analysis	nan	RECRUITING
The Role of TBC1D4 in Exercise- and Insulin-induced Glucose Metabolism in Human Skeletal Muscle	nan	COMPLETED
Transcutaneous Electrical Diaphragmatic Stimulation in Critically Ill Elderly Patients	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a MYL4 binder may also engage these)

Protein	Name	Similarity
F1RRT2	—	1.000	F1RRT2 →
P08590	—	0.997	P08590 →
P09542	—	0.996	P09542 →
Q5R887	—	0.995	Q5R887 →
P09541	—	0.993	P09541 →
P02606	—	0.992	P02606 →
P17209	—	0.991	P17209 →
P16409	—	0.991	P16409 →
P85100	—	0.990	P85100 →
P09540	—	0.990	P09540 →
P02600	—	0.988	P02600 →
P05977	—	0.987	P05977 →
P05976	—	0.986	P05976 →
P02602	—	0.986	P02602 →
P02604	—	0.986	P02604 →
A0JNJ5	—	0.985	A0JNJ5 →
P82159	—	0.982	P82159 →
Q6P0G6	—	0.979	Q6P0G6 →
Q8CI43	—	0.977	Q8CI43 →
P14649	—	0.976	P14649 →
P02605	—	0.960	P02605 →
P82160	—	0.953	P82160 →
Q6P8Y1	—	0.945	Q6P8Y1 →
Q9QW07	—	0.944	Q9QW07 →
P47728	—	0.942	P47728 →
A0A7U2QYM2	—	0.942	A0A7U2QYM2 →
Q8WWF8	—	0.942	Q8WWF8 →
Q24756	—	0.942	Q24756 →
Q24654	—	0.942	Q24654 →
Q08331	—	0.942	Q08331 →