MYO3B

Myosin-IIIb · Q8WXR4 · MYO3B on Sugi Atlas →

181 patent compounds predicted against MYO3B, 170 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL20762768 SCHEMBL20762768 1.00 1/20
SCHEMBL22026540 SCHEMBL22026540 1.00 1/20
SCHEMBL22026543 SCHEMBL22026543 1.00 1/20
SCHEMBL29779922 SCHEMBL29779922 1.00 1/20
SCHEMBL20762903 SCHEMBL20762903 0.92 1/20
SCHEMBL20762935 SCHEMBL20762935 0.91 1/20
SCHEMBL20762724 SCHEMBL20762724 0.90 1/20
SCHEMBL20762737 SCHEMBL20762737 0.89 1/20
SCHEMBL22065430 SCHEMBL22065430 0.89 1/20
SCHEMBL22026524 SCHEMBL22026524 0.89 1/20
SCHEMBL29779920 SCHEMBL29779920 0.89 1/20
SCHEMBL29779926 SCHEMBL29779926 0.89 1/20
SCHEMBL20763374 SCHEMBL20763374 0.88 1/20
SCHEMBL20762799 SCHEMBL20762799 0.86 1/20
SCHEMBL20762902 SCHEMBL20762902 0.86 1/20
SCHEMBL20763141 SCHEMBL20763141 0.86 1/20
SCHEMBL20763482 SCHEMBL20763482 0.86 1/20
SCHEMBL22026542 SCHEMBL22026542 0.86 1/20
SCHEMBL22026544 SCHEMBL22026544 0.86 1/20
SCHEMBL22066361 SCHEMBL22066361 0.86 1/20

Clinical trials — most relevant to MYO3B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Evaluating MED2005 & Nitrostat Bioavailability PHASE1COMPLETED
Transcutaneous Functional Magnetic Muscle Stimulation in Critically Ill nanUNKNOWN
Genetic Testing in Primary Congenital Glaucoma Patients nanUNKNOWN
Natural History Study for Patients With Nemaline Myopathy in Belgium nanNOT_YET_RECRUITING
Pediatric Evaluation and Registry for Liver Cholestasis in Canada nanRECRUITING
Characteristics of Nondystrophic Myotonias nanCOMPLETED
Molecular and Genetic Studies of Congenital Myopathies nanRECRUITING
Phenotype - Genotype Correlation in a Sample of Egyptian Patients With Congenital Myopathies and Congenital Muscular Dystrophies nanRECRUITING
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Mapping of End Stage Renal Disease Genetic Susceptibility in African Americans by Admixture Linkage Disequilibrium nanCOMPLETED
Congenital Muscle Disease Study of Patient and Family Reported Medical Information nanRECRUITING
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia nanCOMPLETED
Changes of Motor Function Tests in Congenital Myopathy Subjects Treated With Oral Salbutamol as Compared to no Treatment nanCOMPLETED
Role of Ultrasound in Diagnosis of Muscle Diseases nanCOMPLETED
Myotubular and Centronuclear Myopathy Patient Registry nanRECRUITING
Cardiac Arrhythmias and Sudden Death in Patients Affected With Laminopathies nanUNKNOWN
CoMPaSS-NMD - Computational Models for New Patients Stratification Strategies of HNMD nanENROLLING_BY_INVITATION
Pediatric Cardiomyopathy Mutation Analysis nanRECRUITING
MYO-SHARE: MYO-MRI in Neuromuscular Diseases nanENROLLING_BY_INVITATION
Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS) nanUNKNOWN
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
Chronic Muscle Disuse in the Elderly nanCOMPLETED
The Prevalence of RYR1-related Disease nanNOT_YET_RECRUITING
LAMA2-related Muscular Dystrophy Brain Study nanWITHDRAWN
Influence of Sarcopenia on the Course of the Diseases nanRECRUITING
3D-Microscopic Muscle Architecture in Cerebral Palsy nanRECRUITING
A Multicenter Phenotype-Genotype Analysis of LGMD Patients in China nanENROLLING_BY_INVITATION
Multiparametric Ultrafast Ultrasound Biomarkers for Duchenne and Becker Muscular Dystrophies nanRECRUITING
Regulation of Muscle Protein Phenotype in Humans With Obesity nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MYO3B binder may also engage these)

ProteinNameSimilarity
Q1EG27 1.000 Q1EG27 →
Q8K3H5 0.999 Q8K3H5 →
MYO3A Myosin-IIIa 0.994 landscape →
Q9V3Z6 0.993 Q9V3Z6 →
A5PF48 0.991 A5PF48 →
Q99MZ6 0.989 Q99MZ6 →
P91443 0.989 P91443 →
P97479 0.989 P97479 →
A7E2Y1 0.988 A7E2Y1 →
Q8N1T3 0.988 Q8N1T3 →
Q6GPA1 0.988 Q6GPA1 →
Q28970 0.988 Q28970 →
F8VQB6 0.987 F8VQB6 →
Q6PIF6 0.987 Q6PIF6 →
Q622K8 0.987 Q622K8 →
Q29P71 0.987 Q29P71 →
Q01989 0.986 Q01989 →
Q9HD67 0.986 Q9HD67 →
Q5SUA5 0.985 Q5SUA5 →
A2AQP0 0.985 A2AQP0 →
P79114 0.985 P79114 →
Q9Y2K3 0.984 Q9Y2K3 →
Q13402 0.984 Q13402 →
Q17LW0 0.984 Q17LW0 →
D3ZJP6 0.984 D3ZJP6 →
Q5ZMC2 0.984 Q5ZMC2 →
Q63357 0.981 Q63357 →
P47808 0.981 P47808 →
O94832 0.981 O94832 →
Q5SYD0 0.980 Q5SYD0 →