NFXL1

NF-X1-type zinc finger protein NFXL1 · Q6ZNB6 · NFXL1 on Sugi Atlas →

0 patent compounds predicted against NFXL1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to NFXL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study Comparing Two Carboplatin Containing Regimens for Children and Young Adults With Previously Untreated Low Grade Glioma PHASE3ACTIVE_NOT_RECRUITING
A Study to Assess the Safety and Efficacy of 3 Doses of ALX1-11 (50, 75, and 100µg) in the Treatment of Postmenopausal Osteoporosis PHASE2COMPLETED
Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas PHASE2COMPLETED
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
EPOCH-R Chemotherapy Plus Bortezomib to Treat Mantle Cell Lymphoma PHASE2COMPLETED
Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors PHASE2COMPLETED
Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. PHASE2COMPLETED
Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors PHASE2COMPLETED
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma PHASE2COMPLETED
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma PHASE1RECRUITING
Concentration and Activity of Lapatinib in Vestibular Schwannomas EARLY_PHASE1COMPLETED
Detection of IKZF1 Deletion Mutation in Patients With Acute Lymphoblastic Leukemia and Its Impact in Therapy nanUNKNOWN
Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes nanACTIVE_NOT_RECRUITING
Analysis of NF2 Mutations in Radiation-Related Neural Tumors nanCOMPLETED
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
Neurobiology and Treatment of Reading Disability in NF-1 nanCOMPLETED
WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data nanCOMPLETED
Natural History Study of Patients With Neurofibromatosis Type 2 nanRECRUITING
NF2 Natural History Consortium nanUNKNOWN
Natural History Study of GATA2 Deficiency and Related Disorders nanRECRUITING
Prognostic Value of Combined Approach Based on KEAP1/NFE2L2 Mutations and Pre-therapeutic FDG-PET/CT Radiomic Analysis in Advanced Non-small-cell Lung Cancer PDL1 ≥ 50% Treated With Pembrolizumab (PEMBROMIC) nanUNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma nanUNKNOWN
Genetic Evaluation of NF1 and Scoliosis Patients nanCOMPLETED
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics nanCOMPLETED
Clonal Architecture of ASXL1-mutated Myelofibrosis nanRECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Genetic and Functional Analysis of Aplasia Cutis Congenital (ACC) nanRECRUITING
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING
Drivers of Hypoxia-induced Angiogenesis in Tumor Development nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a NFXL1 binder may also engage these)

ProteinNameSimilarity
A0JMY5 1.000 A0JMY5 →
Q9FFK8 0.987 Q9FFK8 →
Q9SY59 0.987 Q9SY59 →
B1AY10 0.986 B1AY10 →
A6QLA0 0.982 A6QLA0 →
Q18034 0.980 Q18034 →
P40798 0.978 P40798 →
Q12986 0.976 Q12986 →
O74853 0.971 O74853 →
Q67YE6 0.971 Q67YE6 →
P53971 0.968 P53971 →
Q4R7U2 0.966 Q4R7U2 →
Q0D5B9 0.966 Q0D5B9 →
Q5ZML4 0.966 Q5ZML4 →
D4A4T9 0.965 D4A4T9 →
Q2IBC3 0.964 Q2IBC3 →
Q9D1P4 0.964 Q9D1P4 →
P47226 0.964 P47226 →
Q9JII7 0.963 Q9JII7 →
Q5U2P3 0.963 Q5U2P3 →
Q6H7P8 0.962 Q6H7P8 →
Q9SCM4 0.962 Q9SCM4 →
Q15326 0.962 Q15326 →
Q7ZXE9 0.962 Q7ZXE9 →
Q07DW1 0.962 Q07DW1 →
P39429 0.961 P39429 →
A0M8U6 0.961 A0M8U6 →
P70191 0.961 P70191 →
Q2QLA1 0.961 Q2QLA1 →
A0M8S5 0.961 A0M8S5 →