NONO

Non-POU domain-containing octamer-binding protein · Q15233 · NONO on Sugi Atlas →

0 patent compounds predicted against NONO, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to NONO by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effects of Insulin Sensitizers in Subjects With Impaired Glucose Tolerance PHASE4COMPLETED
A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients PHASE1/PHASE2WITHDRAWN
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
A Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic Melanoma PHASE1/PHASE2COMPLETED
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
NY-ESO-1 Protein With Montanide and CpG 7909 as Cancer Vaccine in Several Tumors PHASE1COMPLETED
DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia PHASE1COMPLETED
Induced Pluripotent Stem Cell Derived Exosomes for the Treatment of Atopic Dermatitis EARLY_PHASE1UNKNOWN
Prognostic Value of Protein IMP3 Expression in Cervical Cancer nanCOMPLETED
Central Serous Chorioretinopathy Registry and Pachychoroid Observation and Natural History Study nanUNKNOWN
Na+ Channel mRNA Regulation in Heart Failure nanCOMPLETED
Novel Biomarkers in Inflammatory Bowel Disease nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Clinical and Molecular Description of PKD1 and PKD2 Mutation Negative Carriers in ADPKD nanCOMPLETED
Probiotics and Systemic Inflammation in Patients With Metabolic Syndrome and High Cardiovascular Risk nanWITHDRAWN
Identification of Genes and Pathogenesis Involved in Familial Thoracic Aortic Aneurysm nanCOMPLETED
Rare and Atypical Diabetes Network nanRECRUITING
Characterization of Retinal Vascular Disease in Eyes With Mild to Moderate NPDR in Diabetes Type 2 nanCOMPLETED
Brain P-gp and Inflammation in People With Epilepsy nanCOMPLETED
Micro RNA Levels in NAFLD nanUNKNOWN
Orbital Vascular Inflammation in Ischemic Optic Neuropathy and Giant Cell Arteritis nanRECRUITING
Immunophenotyping and Xist Gene in AML nanUNKNOWN
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders nanRECRUITING
Epigenomic Profiling of Circulating Cell-Free DNA (cfDNA) to Characterize the Dynamic Evolution of Molecular Subtypes in Extensive-Stage Small Cell Lung Cancer During First-Line Chemoimmunotherapy nanNOT_YET_RECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
PROSPECT - Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification nanRECRUITING
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
The Etiology and Progression of Brain Tumors nanCOMPLETED
The Role of Vitamin K2 in Preventing Glucocorticoid-Induced Bone Loss in Children With Nephrotic Syndrome nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a NONO binder may also engage these)

ProteinNameSimilarity
Q5RFL9 1.000 Q5RFL9 →
Q1JPY8 1.000 Q1JPY8 →
Q5FVM4 1.000 Q5FVM4 →
Q99K48 1.000 Q99K48 →
Q1LZD9 0.996 Q1LZD9 →
PSPC1 Paraspeckle component 1 0.995 landscape →
Q4KLH4 0.994 Q4KLH4 →
Q8R326 0.991 Q8R326 →
Q5ZK88 0.990 Q5ZK88 →
Q8BHR2 0.987 Q8BHR2 →
Q66H68 0.985 Q66H68 →
A0AV96 0.983 A0AV96 →
Q5R5P4 0.983 Q5R5P4 →
Q3UEB3 0.983 Q3UEB3 →
Q9NQ94 0.983 Q9NQ94 →
Q9GRX4 0.983 Q9GRX4 →
Q8BHS3 0.983 Q8BHS3 →
SYNCRIP Heterogeneous nuclear ribonucleoprotein Q 0.983 landscape →
Q7TMK9 0.983 Q7TMK9 →
Q5ZM16 0.982 Q5ZM16 →
P90978 0.982 P90978 →
Q3B7L8 0.982 Q3B7L8 →
Q8TC92 0.982 Q8TC92 →
Q7ZXB5 0.981 Q7ZXB5 →
O54772 0.981 O54772 →
Q5YD48 0.980 Q5YD48 →
Q91WT8 0.980 Q91WT8 →
Q6DEY7 0.980 Q6DEY7 →
Q923K9 0.980 Q923K9 →
Q9GRW7 0.980 Q9GRW7 →