Sugi Predict

Sugi Predict / Targets / NSF

NSF

Vesicle-fusing ATPase · P46459 · NSF on Sugi Atlas →

0 patent compounds predicted against NSF, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to NSF by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle PHASE2/PHASE3NOT_YET_RECRUITING
The Possible Efficacy and Safety of Lansoprazole Co-administration With Neoadjuvant Chemotherapy in Women With Breast Cancer PHASE3COMPLETED
Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK) PHASE2/PHASE3RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
Copper Histidine Therapy for Menkes Diseases PHASE1/PHASE2COMPLETED
Combination Therapy With Isotretinoin and Tamoxifen Expected to Provide Complete Protection Against Severe Acute Respiratory Syndrome Coronavirus PHASE2UNKNOWN
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Treatment of Temporo-Myofascial Disorder of Muscular Origin Using Botulinum Toxin: A Prospective Study PHASE2UNKNOWN
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
SRT in Comparison to ERT on Immune Aspects and Bone Involvement in Gaucher Disease nanUNKNOWN
Study of Chediak-Higashi Syndrome nanRECRUITING
Screening of Lysosomal Storage Disorders Diseases in Minority Groups nanUNKNOWN
Biomarker for Sanfilippo Type A-B-C-D Disease (BioSanfilippo) nanWITHDRAWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
A Study to Evaluate and Characterize the Effect of Pharmacological Chemicals on Blood From Patients With Gaucher Disease nanCOMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Insulin Detemir in Obesity Management nanACTIVE_NOT_RECRUITING
Improving Sleep, Sleep-related Outcomes, and Biomarkers in Veterans nanACTIVE_NOT_RECRUITING
Genetic Variation in CLTCL1 and Whole-body Glucose Control nanCOMPLETED
Vacuolar ATPase and Drug Resistance of High Grade Gliomas nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Cellular Pharmacodynamics of Small Molecules in Lysosomal Storage Disorders nanUNKNOWN
A Study of Circulating Exosome Proteomics In Gallbladder Carcinoma Patients nanUNKNOWN
Mitoquines in COPD nanUNKNOWN
Dopamine Function in Developmental Stuttering nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a NSF binder may also engage these)

ProteinNameSimilarity
Q9QUL6 — 1.000 Q9QUL6 →
P18708 — 1.000 P18708 →
Q5R410 — 1.000 Q5R410 →
P46461 — 0.999 P46461 →
P46460 — 0.999 P46460 →
P54351 — 0.999 P54351 →
Q0DGP6 — 0.997 Q0DGP6 →
Q9M0Y8 — 0.993 Q9M0Y8 →
Q75JI3 — 0.990 Q75JI3 →
Q94392 — 0.987 Q94392 →
Q9P7Q4 — 0.986 Q9P7Q4 →
Q0VD48 — 0.985 Q0VD48 →
P03974 — 0.984 P03974 →
P18759 — 0.984 P18759 →
Q9C8J4 — 0.982 Q9C8J4 →
Q9U2G0 — 0.981 Q9U2G0 →
P34732 — 0.981 P34732 →
I0IUP3 — 0.981 I0IUP3 →
Q8CC88 — 0.981 Q8CC88 →
Q21029 — 0.980 Q21029 →
P46467 — 0.980 P46467 →
Q503W7 — 0.980 Q503W7 →
Q8MJC6 — 0.980 Q8MJC6 →
Q9SF37 — 0.980 Q9SF37 →
Q9UN37 — 0.980 Q9UN37 →
Q793F9 — 0.979 Q793F9 →
Q8WQC9 — 0.979 Q8WQC9 →
Q26454 — 0.979 Q26454 →
Q9FJR0 — 0.979 Q9FJR0 →
Q9UJA3 — 0.979 Q9UJA3 →