OGFOD1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Vadadustat (SCHEMBL1920738)	1.00	1/20
SCHEMBL3419112	1.00	1/20
SCHEMBL3421361	1.00	1/20
SCHEMBL3422096	1.00	1/20
SCHEMBL3422098	1.00	1/20
SCHEMBL3423522	1.00	1/20
SCHEMBL3703019	1.00	1/20
Hydrochloric Acid (SCHEMBL3703018)	0.98	1/20
SCHEMBL3419140	0.97	1/20
SCHEMBL3421189	0.97	1/20
SCHEMBL3423425	0.97	1/20
Bicarbonate (SCHEMBL15419071)	0.97	1/20
Vadadustat (SCHEMBL1921291)	0.89	1/20
SCHEMBL3419490	0.88	1/20
SCHEMBL3419275	0.86	1/20
SCHEMBL3422104	0.86	1/20
SCHEMBL3424056	0.86	1/20
SCHEMBL3424343	0.86	1/20
SCHEMBL14980827	0.85	1/20
SCHEMBL3418320	0.83	1/20

Clinical trials — most relevant to OGFOD1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients	PHASE4	NOT_YET_RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
Study of the Effects of Iron on Lung Blood Pressure at High Altitude	PHASE2	WITHDRAWN
Mitochondrial Function of Immune Cells in Sepsis	nan	COMPLETED
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery	nan	COMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI	nan	RECRUITING
X-Chromosome Inactivation Status and Premature Ovarian Failure	nan	COMPLETED
Prospective Genetic Study in Patients With Ovarian Insufficiency	nan	UNKNOWN
Neurologic Injuries in Adults With Urea Cycle Disorders	nan	COMPLETED
Gyrate Atrophy Ocular and Systemic Study	nan	ACTIVE_NOT_RECRUITING
Primary Hyperoxaluria Mutation Genotyping/Phenotyping	nan	COMPLETED
Predictors of Outcome of Pediatric Renal Transplantation	nan	NOT_YET_RECRUITING
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages	nan	COMPLETED
Drivers of Hypoxia-induced Angiogenesis in Tumor Development	nan	UNKNOWN
Genetic Determinants of Congenital Heart Disease Outcomes	nan	COMPLETED
Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer	nan	RECRUITING
Selecting Hypoxic Tumours for Treatment Modification	nan	RECRUITING
Study of the Effects of Iron Levels on the Lungs at High Altitude	nan	COMPLETED
New Strategies of Genetic Study of Patients With Oculocutaneous Albinism	nan	COMPLETED
Rare Kidney Stone Consortium Biobank	nan	RECRUITING
Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome	nan	UNKNOWN
Exome Sequencing for Atypical Femoral Fractures	nan	COMPLETED
Genetic Analysis of Familial Cases of Premature Ovarian Failure	nan	COMPLETED
Hypoxia Inducible factor1-Alpha Genetic Polymorphism of Obstructive Sleep Apnea	nan	UNKNOWN
Evaluation of Blood Protein O-GlcNAcylation Levels in Children	nan	RECRUITING
Clinical, Cellular, and Molecular Investigation Into Oculocutaneous Albinism	nan	COMPLETED
Role of Polymorphisms in the IL-1 Gene Cluster	nan	COMPLETED
International Registry for Primary Hyperoxaluria	nan	WITHDRAWN
Hemochromatosis and Iron Overload Screening Study (HEIRS)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a OGFOD1 binder may also engage these)

Protein	Name	Similarity
Q5R4R3	—	1.000	Q5R4R3 →
Q3MI03	—	1.000	Q3MI03 →
Q3U0K8	—	1.000	Q3U0K8 →
Q6DE73	—	1.000	Q6DE73 →
Q9I7H9	—	0.992	Q9I7H9 →
P40032	—	0.985	P40032 →
Q11120	—	0.984	Q11120 →
Q95K79	—	0.981	Q95K79 →
Q96BT7	—	0.981	Q96BT7 →
Q80Y20	—	0.980	Q80Y20 →
KAT8	Histone acetyltransferase KAT8	0.979	landscape →
Q8VIJ5	—	0.979	Q8VIJ5 →
KDM5B	Lysine-specific demethylase 5B	0.979	landscape →
A3KP59	—	0.978	A3KP59 →
A3KGZ2	—	0.978	A3KGZ2 →
Q01F03	—	0.978	Q01F03 →
Q07G10	—	0.978	Q07G10 →
C3XRY1	—	0.978	C3XRY1 →
Q5XHF8	—	0.978	Q5XHF8 →
A1A4L5	—	0.977	A1A4L5 →
Q09879	—	0.977	Q09879 →
OGA	Protein O-GlcNAcase	0.977	landscape →
Q7K4H4	—	0.977	Q7K4H4 →
KDM5D	Lysine-specific demethylase 5D	0.977	landscape →
Q9QXG2	—	0.977	Q9QXG2 →
B4GUZ2	—	0.977	B4GUZ2 →
Q8WUF8	—	0.977	Q8WUF8 →
A6NC97	—	0.976	A6NC97 →
Q5K651	—	0.976	Q5K651 →
Q14AI0	—	0.976	Q14AI0 →