Sugi Predict

Sugi Predict / Targets / OTUD7B

OTUD7B

OTU domain-containing protein 7B · Q6GQQ9 · OTUD7B on Sugi Atlas →

5,082 patent compounds predicted against OTUD7B, 1,854 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL13342749 SCHEMBL13342749 0.56 17/20
SCHEMBL13368666 SCHEMBL13368666 0.56 15/20
SCHEMBL17525116 SCHEMBL17525116 0.53 15/20
SCHEMBL17252079 SCHEMBL17252079 0.44 15/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL6641338) 0.52 12/20
SCHEMBL11245424 SCHEMBL11245424 0.34 12/20
SCHEMBL17524925 SCHEMBL17524925 0.53 11/20
SCHEMBL14343755 SCHEMBL14343755 0.56 10/20
SCHEMBL14941425 SCHEMBL14941425 0.59 8/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL3185718) 0.52 8/20
SCHEMBL12747572 SCHEMBL12747572 0.40 8/20
SCHEMBL12747570 SCHEMBL12747570 0.37 8/20
SCHEMBL1466318 SCHEMBL1466318 0.36 8/20
SCHEMBL14941419 SCHEMBL14941419 0.56 7/20
SCHEMBL2604301 SCHEMBL2604301 0.54 7/20
SCHEMBL17525094 SCHEMBL17525094 0.57 6/20
SCHEMBL17525096 SCHEMBL17525096 0.57 6/20
SCHEMBL5482326 SCHEMBL5482326 0.42 6/20
SCHEMBL3028186 SCHEMBL3028186 0.34 6/20
SCHEMBL5359875 SCHEMBL5359875 0.47 5/20

Clinical trials — most relevant to OTUD7B by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit PHASE2/PHASE3WITHDRAWN
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
Infliximab Therapy for Dolichoectactic Vertebrobasilar Aneurysms PHASE1/PHASE2RECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human nanUNKNOWN
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Transcriptional and Epigenetic Program of PCOS Women nanACTIVE_NOT_RECRUITING
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients nanUNKNOWN
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1 nanRECRUITING
Genetic Analysis of Birt Hogg-Dube Syndrome and Characterization of Predisposition to Kidney Cancer nanRECRUITING
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
RNA Cloning and Visualization in Human Atherosclerosis nanCOMPLETED
Genetics and Environment iNtersection In the ALS-FTD Spectrum: an Italian Twins Cohort studY With a Multi-Omics Approach nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Modulation of Genes Responsible for Cilia Length by Exposure to Cigarette Smoke nanCOMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
RNA Assays for Endometriosis Detection and Diagnosis nanENROLLING_BY_INVITATION
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Establishment of a Prospective Clinical-biological Database nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a OTUD7B binder may also engage these)

ProteinNameSimilarity
B2RUR8 — 1.000 B2RUR8 →
Q8R554 — 0.991 Q8R554 →
Q8TE49 — 0.988 Q8TE49 →
P49140 — 0.985 P49140 →
Q8K2L8 — 0.985 Q8K2L8 →
Q80TJ7 — 0.984 Q80TJ7 →
Q8K4S7 — 0.983 Q8K4S7 →
Q62925 — 0.983 Q62925 →
Q80W04 — 0.983 Q80W04 →
Q4VGL6 — 0.983 Q4VGL6 →
Q62415 — 0.982 Q62415 →
Q13905 — 0.982 Q13905 →
Q02225 — 0.982 Q02225 →
PTPN14 Tyrosine-protein phosphatase non-receptor type 14 0.982 landscape →
Q3TTA7 — 0.982 Q3TTA7 →
Q99PU7 — 0.982 Q99PU7 →
Q5XJV7 — 0.981 Q5XJV7 →
Q6NRE7 — 0.981 Q6NRE7 →
Q6NUC6 — 0.981 Q6NUC6 →
Q5PQS6 — 0.981 Q5PQS6 →
Q66IV1 — 0.981 Q66IV1 →
Q8C3F2 — 0.980 Q8C3F2 →
P0CH95 — 0.980 P0CH95 →
Q6DEZ2 — 0.980 Q6DEZ2 →
P0C090 — 0.980 P0C090 →
Q28C33 — 0.980 Q28C33 →
Q9Z136 — 0.980 Q9Z136 →
Q9H694 — 0.980 Q9H694 →
P53349 — 0.980 P53349 →
Q8K245 — 0.980 Q8K245 →