OXTR — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Retosiban (SCHEMBL230301)	1.00	20/20
SCHEMBL930472	1.00	20/20
SCHEMBL930718	1.00	20/20
SCHEMBL930950	1.00	20/20
SCHEMBL931371	1.00	20/20
SCHEMBL931674	0.83	20/20
SCHEMBL930759	0.82	20/20
SCHEMBL930506	0.81	20/20
SCHEMBL930550	0.80	20/20
SCHEMBL931011	0.80	20/20
SCHEMBL931377	0.80	20/20
SCHEMBL930962	0.79	20/20
SCHEMBL232783	0.79	20/20
SCHEMBL233458	0.79	20/20
SCHEMBL930568	0.78	20/20
SCHEMBL930910	0.77	20/20
SCHEMBL931071	0.76	20/20
SCHEMBL931562	0.74	20/20
SCHEMBL931105	0.73	20/20
SCHEMBL931119	0.71	20/20

Clinical trials — most relevant to OXTR by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Methods to Reduce Blood Loss in Abdominal Myomectomy	PHASE4	UNKNOWN
Carbetocin Monotherapy Versus Carbetocin Plus Oxytocin Infusion in Elective Cesarean Delivery: A Non-Inferiority Trial	PHASE4	NOT_YET_RECRUITING
Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep	PHASE3	COMPLETED
Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study	PHASE2/PHASE3	COMPLETED
Effects of Intranasal Oxytocin on Sexual Well-Being in Patients With Arginine Vasopressin Deficiency and Healthy Controls	PHASE2	RECRUITING
Study of Oxytocin in Autism to Improve Reciprocal Social Behaviors	PHASE2	COMPLETED
Oxytocin on Cold Water Task Performance and Recovery	PHASE2	COMPLETED
Oxytocin Substitution Therapy in Patients With Central Diabetes Insipidus	PHASE2	RECRUITING
Administrating Oxytocin to Treat Treatment Schizophrenia and Schizo-affective Patients	PHASE2	UNKNOWN
Oxytocin for Oxidative Stress and Inflammation	PHASE2	COMPLETED
Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin	PHASE2	COMPLETED
Intranasal Oxytocin as Enhancer of Psychotherapy Outcomes in Severe Mental Illness	PHASE2	ACTIVE_NOT_RECRUITING
Oxytocin and Social Cognition	PHASE1	COMPLETED
Oxytocin Modulation of Startle Reactivity to Social Stimuli and Moral Decision Making	PHASE1	COMPLETED
Effects of Oxytocin Dose Frequency on Behavioral and Neural Responses	PHASE1	UNKNOWN
Oxytocin in Alcohol Use Disorder	PHASE1	WITHDRAWN
Effect of Oxytocin on Masked Facial Expressions: an fMRI Study	EARLY_PHASE1	COMPLETED
Induction of Labor With Oxytocin: When Should Oxytocin be Held?	nan	COMPLETED
Empathy, Psychopathy and Autism: Behavioural Associations and the Role of an Oxytocin Receptor Polymorphism in a Non-clinical Adult Population	nan	COMPLETED
Circulating Oxytocin Changes in Response to MDMA vs. Placebo in Adult Patients With Autism Spectrum Disorder and Matched Healthy Controls	nan	NOT_YET_RECRUITING
The Effect of Early Dyadic Psychotherapy for Mothers Suffering From PPD on Oxytocin Level and on Childrens' Emotional Development	nan	UNKNOWN
Oxytocin Receptor Expression in Pregnancy	nan	ACTIVE_NOT_RECRUITING
A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity	nan	COMPLETED
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD	nan	COMPLETED
Oxytocin in Cocaine Dependence	nan	COMPLETED
Does Acute Oxytocin Administration Enhance Social Cognition in Individuals With Schizophrenia?	nan	COMPLETED
Oxytocin-Augmented Group Psychotherapy for Patients With Schizophrenia - an Oxytocin-dose Comparison	nan	RECRUITING
Maternal Speech Decreases Pain Scores and Increases Oxytocin Levels in Preterm Infants During Painful Procedures	nan	COMPLETED
Characterization of Microbial, Immune and Epigenetic Biomarkers for Major Depressive Disorder and ECT Treatment	nan	UNKNOWN
Early Parenting Intervention: Bio-behavioral Outcomes in Infants With Neurodevelopmental Disabilities	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a OXTR binder may also engage these)

Protein	Name	Similarity
P32306	—	1.000	P32306 →
P56494	—	1.000	P56494 →
P97926	—	0.997	P97926 →
P70536	—	0.996	P70536 →
P56449	—	0.996	P56449 →
Q28756	—	0.995	Q28756 →
P48043	—	0.977	P48043 →
Q9WTV8	—	0.976	Q9WTV8 →
Q9WTV9	—	0.975	Q9WTV9 →
AVPR1A	Vasopressin V1a receptor	0.972	landscape →
O88721	—	0.969	O88721 →
Q00788	—	0.969	Q00788 →
P30560	—	0.969	P30560 →
O77808	—	0.967	O77808 →
Q62463	—	0.967	Q62463 →
P32307	—	0.966	P32307 →
AVPR2	Vasopressin V2 receptor	0.966	landscape →
O42329	—	0.960	O42329 →
AVPR1B	Vasopressin V1b receptor	0.959	landscape →
P48044	—	0.958	P48044 →
P48974	—	0.957	P48974 →
Q9WU02	—	0.957	Q9WU02 →
Q95JG1	—	0.957	Q95JG1 →
Q95MH6	—	0.956	Q95MH6 →
Q95MG6	—	0.955	Q95MG6 →
Q90252	—	0.953	Q90252 →
Q90334	—	0.952	Q90334 →
Q5DUB2	—	0.947	Q5DUB2 →
Q90352	—	0.944	Q90352 →
P16610	—	0.943	P16610 →