PAF1

RNA polymerase II-associated factor 1 homolog · Q8N7H5 · PAF1 on Sugi Atlas →

0 patent compounds predicted against PAF1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PAF1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients PHASE3UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
A Study of Cediranib and Olaparib at the Time Ovarian Cancer Worsens on Olaparib PHASE2COMPLETED
Pembrolizumab (MK-3475) in MM Patients With Residual Disease PHASE2COMPLETED
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab PHASE1/PHASE2RECRUITING
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
AZD2281 and Cisplatin Plus Gemcitabine to Treat Solid Tumor Cancers PHASE1COMPLETED
ZEN003694 Combined With Niraparib in Patients With Metastatic or Recurrent Solid Tumors PHASE1WITHDRAWN
PET Imaging of PARP Activity in Cancer EARLY_PHASE1UNKNOWN
Platelet-activating Factor Acetylhydrolase (Paf-ah) Gene Expression nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Molecular Mechanism of Nasopharyngeal Carcinoma nanUNKNOWN
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients nanUNKNOWN
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Research on the Early and Prognosis Diagnosis of Vascular Dementia nanRECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) nanCOMPLETED
Collection of Blood Samples for DNA in Motor Neuron Disease nanCOMPLETED
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
SCOR in Neurobiology of Sleep--Intermediate Traits for Sleep Apnea nanCOMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma nanCOMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PAF1 binder may also engage these)

ProteinNameSimilarity
Q2KJ14 1.000 Q2KJ14 →
Q4V886 1.000 Q4V886 →
Q8K2T8 1.000 Q8K2T8 →
Q6P2Y1 0.997 Q6P2Y1 →
Q5RAX0 0.997 Q5RAX0 →
Q4U0S5 0.996 Q4U0S5 →
A2BD83 0.995 A2BD83 →
GTF2F1 General transcription factor IIF subunit 1 0.985 landscape →
Q3THK3 0.980 Q3THK3 →
Q6AY96 0.978 Q6AY96 →
Q5EA53 0.975 Q5EA53 →
Q8CFC7 0.974 Q8CFC7 →
Q5HZB6 0.973 Q5HZB6 →
Q9SU25 0.972 Q9SU25 →
Q04870 0.972 Q04870 →
Q53F19 0.970 Q53F19 →
LEO1 RNA polymerase-associated protein LEO1 0.969 landscape →
Q9Z315 0.968 Q9Z315 →
Q9R1C0 0.968 Q9R1C0 →
Q91WD1 0.968 Q91WD1 →
Q5XIW8 0.967 Q5XIW8 →
Q5ZHP7 0.967 Q5ZHP7 →
Q8N2M8 0.967 Q8N2M8 →
A0JNI5 0.966 A0JNI5 →
Q6PII3 0.966 Q6PII3 →
Q5XJE5 0.966 Q5XJE5 →
Q6R1L1 0.965 Q6R1L1 →
Q91ZD6 0.965 Q91ZD6 →
Q641X2 0.965 Q641X2 →
Q8WU90 0.964 Q8WU90 →