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PANK2

Pantothenate kinase 2, mitochondrial · Q9BZ23 · PANK2 on Sugi Atlas →

2 patent compounds predicted against PANK2, 2 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1079094 SCHEMBL1079094 0.41 1/20
SCHEMBL3541648 SCHEMBL3541648 0.41 1/20

Clinical trials — most relevant to PANK2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer PHASE4WITHDRAWN
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction PHASE2/PHASE3UNKNOWN
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome PHASE1/PHASE2COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension PHASE2NOT_YET_RECRUITING
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
Bempedoic Acid Therapy for Polycystic Kidney Disease PHASE2NOT_YET_RECRUITING
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Phase 1a Single Ascending Dose Study of MIB-725 in Healthy Adults PHASE1RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation nanCOMPLETED
Effect of Age on Glucose and Lipid Metabolism nanCOMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort nanRECRUITING
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells nanRECRUITING
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
The Genetics of Diabetes in Southern California Chinese Americans nanWITHDRAWN
Warfarin Effects on Male Fertility After Cardiac Surgery nanNOT_YET_RECRUITING
Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Damage-Associated Molecular Patterns (mtDAMPs) and Senescence-Associated Secretory Phenotype (SASP) nanNOT_YET_RECRUITING
Outcome of Use of a Novel Modulator of Oxidative Phosphorylation on Kidney Function in Patients With Progressive Chronic Kidney Disease nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PANK2 binder may also engage these)

ProteinNameSimilarity
PANK1 Pantothenate kinase 1 0.994 landscape →
Q7M753 — 0.993 Q7M753 →
Q8K4K6 — 0.990 Q8K4K6 →
Q9CAE3 — 0.988 Q9CAE3 →
Q7XPE8 — 0.987 Q7XPE8 →
Q6YYZ1 — 0.987 Q6YYZ1 →
D3YWQ0 — 0.987 D3YWQ0 →
Q8TBC3 — 0.987 Q8TBC3 →
Q9VLA1 — 0.987 Q9VLA1 →
Q4D9P2 — 0.987 Q4D9P2 →
Q580W5 — 0.986 Q580W5 →
Q8L6H7 — 0.986 Q8L6H7 →
Q5VVW2 — 0.986 Q5VVW2 →
Q6T5K2 — 0.986 Q6T5K2 →
F1MAB7 — 0.986 F1MAB7 →
A2WYE9 — 0.986 A2WYE9 →
Q8VXV7 — 0.986 Q8VXV7 →
Q8BJM7 — 0.985 Q8BJM7 →
Q9FH80 — 0.985 Q9FH80 →
A3KMV1 — 0.985 A3KMV1 →
Q7XUR2 — 0.985 Q7XUR2 →
MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 0.985 landscape →
Q9LJK1 — 0.985 Q9LJK1 →
F5HB62 — 0.985 F5HB62 →
Q8W3F9 — 0.985 Q8W3F9 →
Q5VRL3 — 0.985 Q5VRL3 →
F4HX15 — 0.985 F4HX15 →
Q9D5Z5 — 0.985 Q9D5Z5 →
Q9C6G0 — 0.985 Q9C6G0 →
O23461 — 0.985 O23461 →