PCCA

Propionyl-CoA carboxylase alpha chain, mitochondrial · P05165 · PCCA on Sugi Atlas →

0 patent compounds predicted against PCCA, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PCCA by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparative Study of Dietary and Immunological Management of Refractory Epilepsy in Children PHASE4UNKNOWN
Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency: PHASE3ACTIVE_NOT_RECRUITING
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients PHASE2COMPLETED
Metabolic Cofactor Supplementation in Obese Patients With Non-Alcoholic Fatty Liver Disease PHASE2COMPLETED
Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI) PHASE2RECRUITING
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC PHASE1/PHASE2UNKNOWN
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
AAVrh10-PCCA Gene Therapy for Propionic Acidemia PHASE1RECRUITING
A Retrospective Study to Characterize Participants With Propionic Acidemia nanRECRUITING
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Microbiome Composition and Biomarker Discovery in Refractory Pediatric Epilepsy nanWITHDRAWN
11C-Acetate PET/CT Non-FDG-Avid Tumors nanUNKNOWN
Evaluation of Hydroxymethylbutyrate Supplementation in Lung Transplant Candidates Receiving Pulmonary Rehabilitation nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Mitochondrial Assessment in Critical Ill Patients in Intensive Care nanNOT_YET_RECRUITING
Development of Novel Therapies for NIDDM nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
KETO-TUMOR: a Study on Brain Tumors and Central Obesity nanRECRUITING
Mitoquines in COPD nanUNKNOWN
Triheptanoin (UX007) to Treat Citrate Transporter Deficiency nanNO_LONGER_AVAILABLE
Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis nanCOMPLETED
Ketogenic Diet Therapy for Autism Spectrum Disorder nanCOMPLETED
Isoleucine Intake and Intermediary Metabolism in Type 2 Diabetes nanCOMPLETED
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients nanRECRUITING
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
Hepatic Energy Fluxes in NASH and NAS Patients nanACTIVE_NOT_RECRUITING
Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids nanCOMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men nanRECRUITING
Effects of Parenteral L-carnitine Supplementation in Premature Neonates nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PCCA binder may also engage these)

ProteinNameSimilarity
P0DTA4 1.000 P0DTA4 →
P14882 1.000 P14882 →
Q42777 1.000 Q42777 →
Q91ZA3 0.999 Q91ZA3 →
Q2QMG2 0.998 Q2QMG2 →
Q612F5 0.997 Q612F5 →
Q99MR8 0.997 Q99MR8 →
Q54KE6 0.995 Q54KE6 →
Q42523 0.995 Q42523 →
Q38970 0.995 Q38970 →
Q8S6N5 0.994 Q8S6N5 →
Q96RQ3 0.994 Q96RQ3 →
O94313 0.994 O94313 →
Q19842 0.993 Q19842 →
Q5I0C3 0.993 Q5I0C3 →
Q5LUF3 0.992 Q5LUF3 →
B9HBA8 0.992 B9HBA8 →
B9FK36 0.992 B9FK36 →
P00927 0.992 P00927 →
Q39735 0.992 Q39735 →
B9N843 0.991 B9N843 →
P54889 0.990 P54889 →
Q9UUE1 0.990 Q9UUE1 →
Q8X1T3 0.990 Q8X1T3 →
P09445 0.990 P09445 →
A0A4P8DJE6 0.990 A0A4P8DJE6 →
Q8C196 0.990 Q8C196 →
P93028 0.990 P93028 →
P32327 0.990 P32327 →
P22221 0.990 P22221 →