PCK2

Phosphoenolpyruvate carboxykinase [GTP], mitochondrial · Q16822 · PCK2 on Sugi Atlas →

0 patent compounds predicted against PCK2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PCK2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of a Basal/Pre-Meal Insulin Strategy (Detemir/Aspart) on Insulin Secretion and Action in Type 2 Diabetes PHASE4COMPLETED
Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone. PHASE4COMPLETED
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Bempedoic Acid Therapy for Polycystic Kidney Disease PHASE2NOT_YET_RECRUITING
Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI) PHASE2RECRUITING
The Effect of Addition of Metformin In Obese Non- Diabetic Patients With Heart Failure With Preserved Ejection Fraction PHASE2UNKNOWN
Effect of Pioglitazone Administered to Patients With Adrenomyeloneuropathy PHASE2COMPLETED
Prehabilitation in Liver Surgery PHASE1COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation nanCOMPLETED
Mitoquines in COPD nanUNKNOWN
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation? nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort nanRECRUITING
Mechanisms of the Effect of Physical Activity on the Adaptation to a High-Fat Diet nanCOMPLETED
Efficacy of High Dose Albumin Therapy in Improving Liver Transplant-free Survival in Patients With Acute Decompensation of Cirrhosis nanUNKNOWN
McArdle Disease Treatment by Ketogenic Diet nanCOMPLETED
In and ex Vivo Mitochondrial Function of the Heart nanCOMPLETED
Mitochondrial Dysfunction in Diabetes nanCOMPLETED
Metabolic Flexibility in Patients With Early Triple-negative Breast Cancer nanACTIVE_NOT_RECRUITING
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2 nanUNKNOWN
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
METabolic PROFILE of Hepatocarcinoma and Pancreatic Tumors nanRECRUITING
Effect of Age on Glucose and Lipid Metabolism nanCOMPLETED
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PCK2 binder may also engage these)

ProteinNameSimilarity
Q0RCJ7 1.000 Q0RCJ7 →
Q2J645 1.000 Q2J645 →
Q8BH04 1.000 Q8BH04 →
Q62FI7 1.000 Q62FI7 →
Q5L4X1 0.999 Q5L4X1 →
Q2L1L0 0.999 Q2L1L0 →
Q63VB7 0.999 Q63VB7 →
B4UDY7 0.999 B4UDY7 →
Q73TS2 0.999 Q73TS2 →
Q82I71 0.999 Q82I71 →
B2U804 0.999 B2U804 →
P20007 0.998 P20007 →
Q8KAD1 0.998 Q8KAD1 →
Q5P2P8 0.998 Q5P2P8 →
Q6AGS4 0.998 Q6AGS4 →
O83159 0.998 O83159 →
Q256B8 0.998 Q256B8 →
Q8Y3G3 0.998 Q8Y3G3 →
Q9Z755 0.998 Q9Z755 →
P07379 0.998 P07379 →
B2JJT8 0.997 B2JJT8 →
B8J7G1 0.997 B8J7G1 →
A1U995 0.997 A1U995 →
Q2IFT1 0.997 Q2IFT1 →
Q08262 0.997 Q08262 →
Q9Z2V4 0.997 Q9Z2V4 →
Q5R5J1 0.997 Q5R5J1 →
P65687 0.997 P65687 →
A4FQV7 0.997 A4FQV7 →
A0QP32 0.997 A0QP32 →