Sugi Predict

Sugi Predict / Targets / PFAS

PFAS

Phosphoribosylformylglycinamidine synthase · O15067 · PFAS on Sugi Atlas →

0 patent compounds predicted against PFAS, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PFAS by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effectiveness of Seasonal Malaria Chemoprevention in Nampula Province, Mozambique: Type Two Hybrid Implementation Study PHASE4UNKNOWN
Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum PHASE3COMPLETED
A Phase II Study of TX Regimen as First-line Treatment for Asian Elderly Patients With Advanced Adenocarcinoma of Lung PHASE2COMPLETED
Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA) PHASE2WITHDRAWN
Metronomic Chemotherapy With Tegafur/Uracil for Head and Neck Squamous Cell Carcinoma PHASE2UNKNOWN
Pemetrexed in Combination With Erlotinib as a Salvage Treatment in Patients With Metastatic Biliary Tract Cancer (BTC) Who Failed Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective Study PHASE2UNKNOWN
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome PHASE2RECRUITING
Prospective Phase II Randomized Trial of Postoperative Adjuvant Chemotherapy in Patients With High Risk Colon Cancer PHASE2UNKNOWN
A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure PHASE1COMPLETED
Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors PHASE1COMPLETED
Tumor Response to Pemetrexed Disodium in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Enrolled in Clinical Trial MCCRC-RC0524 nanCOMPLETED
Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) nanSUSPENDED
The Development of Human Immunologic Assays Specific to Folate Receptor Antigen nanUNKNOWN
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
Chest Wall Deformities in Children - Epidemiological Data nanCOMPLETED
SPK Study in Afghanistan nanCOMPLETED
Effects of Dual-Source Carbohydrate Intake and Liver Glycogen Repletion After Overnight Fasting. nanNOT_YET_RECRUITING
Familial Partial Lipodystrophy Study nanCOMPLETED
Assessing Colonic Folate Absorption & Metabolism nanUNKNOWN
Genetic Analysis of Fraser Syndrome and Fryns Syndrome nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Nudge Strategies for DPYD Testing in Patients With Gastrointestinal Cancers Treated With Fluoropyrimidines nanCOMPLETED
PK/PD Investigation of Calciumfolinat in Blood, Tumor and Adjacent Mucosa in Patient With Colon Cancer nanUNKNOWN
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Tonsillotomy or Follow-up in PFAPA Syndrome nanCOMPLETED
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients. nanCOMPLETED
Genetic Markers for Focal Segmental Glomerulosclerosis nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PFAS binder may also engage these)

ProteinNameSimilarity
Q5SUR0 — 1.000 Q5SUR0 →
P35421 — 1.000 P35421 →
Q7N1Z4 — 0.998 Q7N1Z4 →
Q9JXK5 — 0.997 Q9JXK5 →
Q886W6 — 0.997 Q886W6 →
Q9CLW4 — 0.996 Q9CLW4 →
Q1H2I8 — 0.995 Q1H2I8 →
Q88P16 — 0.995 Q88P16 →
Q1CKD2 — 0.995 Q1CKD2 →
Q7MN70 — 0.995 Q7MN70 →
Q9KTN2 — 0.995 Q9KTN2 →
P43847 — 0.995 P43847 →
Q0HX47 — 0.995 Q0HX47 →
Q8DF81 — 0.994 Q8DF81 →
Q9HXN2 — 0.994 Q9HXN2 →
Q0HKU9 — 0.994 Q0HKU9 →
Q57LE6 — 0.994 Q57LE6 →
Q4ZX02 — 0.994 Q4ZX02 →
Q87RW0 — 0.994 Q87RW0 →
Q1C5E7 — 0.994 Q1C5E7 →
Q2SK05 — 0.994 Q2SK05 →
Q48LX3 — 0.993 Q48LX3 →
Q65RJ7 — 0.993 Q65RJ7 →
Q085S1 — 0.993 Q085S1 →
Q3J9F3 — 0.993 Q3J9F3 →
Q4QME6 — 0.993 Q4QME6 →
Q3KHL4 — 0.993 Q3KHL4 →
Q667W1 — 0.993 Q667W1 →
Q31XT0 — 0.993 Q31XT0 →
Q1R8H7 — 0.993 Q1R8H7 →