PFN1

Profilin-1 · P07737 · PFN1 on Sugi Atlas →

0 patent compounds predicted against PFN1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PFN1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Enhancing Effect on Tumour Apoptosis With the Use of Pentoxifylline in Patients With Hodgkin Lymphoma PHASE4UNKNOWN
Treatment of Ectopic Calcification in Fahr's Disease or Syndrome PHASE2RECRUITING
Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. PHASE2COMPLETED
Imaging Regional Lung Defect Severity PHASE1/PHASE2COMPLETED
ERASE - Impact of COVID-19 on Malaria Control nanUNKNOWN
Familial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary Cancers nanRECRUITING
Genetic Analysis of Fraser Syndrome and Fryns Syndrome nanCOMPLETED
PLIN1 Variants in Precocious ACS (SCAPLIN) nanUNKNOWN
Pediatric Evaluation and Registry for Liver Cholestasis in Canada nanRECRUITING
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders nanUNKNOWN
Epithelial Mesenchymal Transition and Periodontitis nanUNKNOWN
Familial Partial Lipodystrophy Study nanCOMPLETED
Risk Factors for Tooth Eruption Diseases nanNOT_YET_RECRUITING
A Longitudinal Systems Biological Analysis of Naturally Acquired Malaria Immunity in Mali nanCOMPLETED
Anthropogenetic Variability in the Group of Individuals With Febrile Seizures nanCOMPLETED
Molecular Analysis of Patients With Neuromuscular Disease nanRECRUITING
Study of Proteus Syndrome and Related Congenital Disorders nanRECRUITING
FA Clinical Outcome Measures nanACTIVE_NOT_RECRUITING
Thoracic Aortic Dilatation Syndromes nanCOMPLETED
A Study to Assess the Genetic Variations in Bile Flow Disorders: Linking Progressive Familial Intrahepatic Cholestasis (PFIC)-Related Genes to Symptoms in Adults With Recurrent Cholestasis in Spain nanRECRUITING
Neurogenetic And Hemodynamic Of Migraine Aura And Pfo nanRECRUITING
Natural History Study of Mitochondrial Myopathy nanRECRUITING
C-Protein in Fatigue and Aging nanRECRUITING
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies. nanRECRUITING
Implementation of Molecular Diagnostic Pathways nanUNKNOWN
Clinical and Biochemical Features for the Identification of Dominant Calpainopathies nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
DeciFace: Decipher the Influence of Ethnic Backgrounds on the Facial Dysmorphic Features of Rare Mendelian Disorders nanRECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
p11 Protein Levels in Patients With Major Depressive Disorder Treated With Citalopram nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PFN1 binder may also engage these)

ProteinNameSimilarity
P62962 1.000 P62962 →
P62963 1.000 P62963 →
Q9EPC6 1.000 Q9EPC6 →
Q5R4E2 1.000 Q5R4E2 →
Q4R4P8 1.000 Q4R4P8 →
Q9JJV2 1.000 Q9JJV2 →
P02584 1.000 P02584 →
P35080 0.997 P35080 →
Q9XF40 0.996 Q9XF40 →
O65809 0.995 O65809 →
Q38904 0.995 Q38904 →
A4GDU3 0.995 A4GDU3 →
Q64LH0 0.995 Q64LH0 →
P0C0Y3 0.995 P0C0Y3 →
Q5EF31 0.995 Q5EF31 →
P0DKF1 0.995 P0DKF1 →
Q93YI9 0.995 Q93YI9 →
P32006 0.995 P32006 →
P0DKF0 0.995 P0DKF0 →
Q9M7M9 0.995 Q9M7M9 →
A4GDT3 0.995 A4GDT3 →
Q9XF41 0.994 Q9XF41 →
P0DKF7 0.994 P0DKF7 →
P0DKF5 0.994 P0DKF5 →
Q5XWE1 0.994 Q5XWE1 →
P25816 0.994 P25816 →
A4GDR3 0.994 A4GDR3 →
Q9SNW7 0.994 Q9SNW7 →
P49233 0.994 P49233 →
P26199 0.994 P26199 →