PHB1

Prohibitin 1 · P35232 · PHB1 on Sugi Atlas →

0 patent compounds predicted against PHB1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PHB1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Betaine and Peroxisome Biogenesis Disorders PHASE3COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder PHASE2WITHDRAWN
Efficacy and Safety of the Treatment of Pyruvate Dehydrogenase Deficiency Patients With Glycerol Phenylbutyrate (RAVICTI) PHASE2RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Glutamine Supplementation in People With Immune Dysregulation EARLY_PHASE1WITHDRAWN
Nicotinamide Riboside and Mitochondrial Biogenesis nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes nanCOMPLETED
The PRE-OP ENERGY Trial nanUNKNOWN
Mapping Disease Pathways for Biliary Atresia nanRECRUITING
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Effects of Acute Energy Deficit and Aerobic Exercise on Muscle Quality nanCOMPLETED
Influence of Diabetic Neuropathy on Activation of Brown Adipose Tissue nanUNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
mTORC1 and Autophagy in Human Brown Adipocytes nanCOMPLETED
Genetic Testing in Primary Congenital Glaucoma Patients nanUNKNOWN
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
The Natural History of Mitochondrial Diseases nanRECRUITING
Purinergic Signaling and the Postmenopausal Heart nanRECRUITING
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Natural History of Familial Cerebral Cavernous Malformations: the CCM_Italia Cohort Study nanRECRUITING
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES) nanRECRUITING
Metabolic Flexibility in Patients With Early Triple-negative Breast Cancer nanACTIVE_NOT_RECRUITING
Mitochondrial Dysfunction in Phelan-McDermid Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PHB1 binder may also engage these)

ProteinNameSimilarity
Q3T165 1.000 Q3T165 →
P67779 1.000 P67779 →
P67778 1.000 P67778 →
P84173 1.000 P84173 →
P24156 0.969 P24156 →
Q28J34 0.960 Q28J34 →
Q6DKC0 0.957 Q6DKC0 →
Q5R7C5 0.956 Q5R7C5 →
ERLIN2 Erlin-2 0.955 landscape →
Q5RCJ9 0.955 Q5RCJ9 →
Q58EG2 0.955 Q58EG2 →
Q5XH03 0.954 Q5XH03 →
Q91X78 0.954 Q91X78 →
Q28DX1 0.953 Q28DX1 →
A3QK16 0.953 A3QK16 →
Q8BFZ9 0.952 Q8BFZ9 →
ERLIN1 Erlin-1 0.950 landscape →
B5DEH2 0.950 B5DEH2 →
Q1RMU4 0.946 Q1RMU4 →
Q9SRH6 0.937 Q9SRH6 →
Q9CAR7 0.928 Q9CAR7 →
Q9BKU4 0.927 Q9BKU4 →
B9N1F9 0.923 B9N1F9 →
Q9FHM7 0.919 Q9FHM7 →
E0CSI1 0.915 E0CSI1 →
Q28007 0.915 Q28007 →
Q6NYG8 0.915 Q6NYG8 →
Q2RAK2 0.914 Q2RAK2 →
O80526 0.914 O80526 →
Q28943 0.913 Q28943 →