PHYKPL

5-phosphohydroxy-L-lysine phospho-lyase · Q8IUZ5 · PHYKPL on Sugi Atlas →

0 patent compounds predicted against PHYKPL, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PHYKPL by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia PHASE3COMPLETED
Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP) PHASE2WITHDRAWN
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
Ketohexokinase Inhibition in NAFLD PHASE2COMPLETED
Safety, Tolerability and Pharmacokinetics of Benfo-Oxythiamine (B-OT) in Healthy Volunteers PHASE1COMPLETED
Assessment of KM-001 - Safety, Tolerability, and Efficacy in Patients With PPPK1 or PC PHASE1COMPLETED
Study Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita Diseases PHASE1COMPLETED
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) nanCOMPLETED
Lysine Oxidation in Response to Arginine Supplementation nanCOMPLETED
Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU) nanRECRUITING
Vulvodynia: Identification of Potential Relevant Biomarkers nanCOMPLETED
Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas nanCOMPLETED
Pyruvate Kinase Deficiency Epidemiological Study (PIECE) nanCOMPLETED
Biomarker for Hypophosphatasia Disease (BioHypophos) nanWITHDRAWN
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease nanRECRUITING
The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia nanRECRUITING
Prevalence of Lysosomal Hydrolase Alpha-glagtosidase Deficiency in Patients With Antiphospholipid Syndrome. nanUNKNOWN
Circulating miRNAs and Bone Microstructure in Adults With Hypophosphatasia nanUNKNOWN
The Role of Sugars in Fat Accumulation in the Liver nanRECRUITING
Comparison of Atherogenic Risk Factors and Efficacy of Nutritional Treatment Among Adult Phenylketonuria Patients nanNOT_YET_RECRUITING
Pyruvate Kinase Deficiency Global Longitudinal Registry nanACTIVE_NOT_RECRUITING
Rare Kidney Stone Consortium Biobank nanRECRUITING
Combined Use of a Medical Device and a Dietary Complement in Patient Urinary pH Control in Patients With an Implanted Double J Stent. nanCOMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Fluorodeoxyglucose Positron Emission Tomography (FDG PET) Findings in Patients With Phenylketonuria Before and After KUVAN Therapy nanCOMPLETED
Dried Fruit and Postprandial Glycemia Trial nanUNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PHYKPL binder may also engage these)

ProteinNameSimilarity
Q8R1K4 0.993 Q8R1K4 →
Q9VU95 0.991 Q9VU95 →
Q8BWU8 0.989 Q8BWU8 →
Q8TBG4 0.989 Q8TBG4 →
Q7SY54 0.989 Q7SY54 →
Q6ZH29 0.986 Q6ZH29 →
Q5E9S4 0.985 Q5E9S4 →
P91408 0.981 P91408 →
Q84P52 0.981 Q84P52 →
O88986 0.980 O88986 →
Q7XN12 0.979 Q7XN12 →
Q01K12 0.978 Q01K12 →
Q21217 0.978 Q21217 →
B8BBZ7 0.978 B8BBZ7 →
P28269 0.977 P28269 →
Q9I6J2 0.977 Q9I6J2 →
O13837 0.977 O13837 →
Q6DEB1 0.977 Q6DEB1 →
P44951 0.976 P44951 →
Q9SR86 0.976 Q9SR86 →
Q01767 0.976 Q01767 →
Q940M2 0.976 Q940M2 →
Q64VX4 0.976 Q64VX4 →
Q7XN11 0.975 Q7XN11 →
Q0P5L8 0.975 Q0P5L8 →
Q6K8E7 0.975 Q6K8E7 →
Q6QUY9 0.975 Q6QUY9 →
P56744 0.974 P56744 →
Q84P54 0.974 Q84P54 →
Q01K11 0.974 Q01K11 →