PICALM

Phosphatidylinositol-binding clathrin assembly protein · Q13492 · PICALM on Sugi Atlas →

0 patent compounds predicted against PICALM, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PICALM by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Pembrolizumab Plus Enfortumab Vedotin in Collecting Duct and Renal Medullary Carcinoma PHASE2RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery EARLY_PHASE1COMPLETED
Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Immune Cell Response to Stimuli nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Genetic Variation in CLTCL1 and Whole-body Glucose Control nanCOMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Nuclear Myosin VI - a Therapeutic Target in Breast Cancer nanUNKNOWN
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Autophagy/Apoptosis Balance in Placental Vascular Pathologies nanRECRUITING
Defining an Obesity QTL on Chromosome 3q nanCOMPLETED
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
The Roles of Neutrophil Elastase in Lung Cancer nanUNKNOWN
Protein Synthesis in the Brain of Patients With Fragile X Syndrome nanCOMPLETED
Open-Label Study of Omega 3 Oil Supplementation for Aging-Related Cognitive Decline nanCOMPLETED
Susceptibility Genes in Autism Spectrum Disorders nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study nanCOMPLETED
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease nanCOMPLETED
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a PICALM binder may also engage these)

ProteinNameSimilarity
O55012 1.000 O55012 →
Q7M6Y3 1.000 Q7M6Y3 →
Q9LPL6 0.994 Q9LPL6 →
Q9XZI6 0.994 Q9XZI6 →
Q8CHU3 0.994 Q8CHU3 →
O75886 0.992 O75886 →
Q9VI75 0.992 Q9VI75 →
Q6BNP6 0.991 Q6BNP6 →
O60167 0.991 O60167 →
P41846 0.991 P41846 →
Q9C9Y1 0.991 Q9C9Y1 →
O43078 0.991 O43078 →
P53309 0.991 P53309 →
Q9FL69 0.991 Q9FL69 →
Q9Z1Z3 0.991 Q9Z1Z3 →
Q0CJV3 0.990 Q0CJV3 →
Q75A30 0.990 Q75A30 →
Q9W1X4 0.990 Q9W1X4 →
A1CEK1 0.990 A1CEK1 →
P34489 0.989 P34489 →
G5EDY0 0.989 G5EDY0 →
Q54TH9 0.989 Q54TH9 →
P47160 0.989 P47160 →
Q6C3L4 0.989 Q6C3L4 →
P38856 0.989 P38856 →
Q54G21 0.988 Q54G21 →
A1DFP5 0.988 A1DFP5 →
P32744 0.988 P32744 →
Q94361 0.988 Q94361 →
Q4WHP5 0.988 Q4WHP5 →