POLR1G

DNA-directed RNA polymerase I subunit RPA34 · O15446 · POLR1G on Sugi Atlas →

0 patent compounds predicted against POLR1G, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to POLR1G by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection PHASE3UNKNOWN
Intracameral Antibiotic Safety Study PHASE3SUSPENDED
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers PHASE1/PHASE2COMPLETED
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients (POLKA) PHASE1/PHASE2RECRUITING
Avelumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer PHASE2UNKNOWN
Durvalumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer PHASE2COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer PHASE2ACTIVE_NOT_RECRUITING
Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
Safety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and Lymphomas PHASE1COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors PHASE1COMPLETED
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors PHASE1ACTIVE_NOT_RECRUITING
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors PHASE1COMPLETED
Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers PHASE1RECRUITING
AZD2281 and Cisplatin Plus Gemcitabine to Treat Solid Tumor Cancers PHASE1COMPLETED
Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer PHASE1ACTIVE_NOT_RECRUITING
Spironolactone and XPB-1 Integrity in the TFIIH Complex nanENROLLING_BY_INVITATION
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Chromosomal Translocations in Chandigarh Police nanCOMPLETED
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) nanCOMPLETED
Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission. nanUNKNOWN
S8814A Biomarkers in Predicting Outcome in Postmenopausal Women With Hormone Receptor-Positive, Node-Positive Breast Cancer Treated With Tamoxifen With or Without Cyclophosphamide, Doxorubicin, and Fluorouracil nanCOMPLETED
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 nanCOMPLETED
DNA Repair Genes and Outcomes in Patients With Stage III NSCLC nanUNKNOWN
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a POLR1G binder may also engage these)

ProteinNameSimilarity
Q76KJ5 0.996 Q76KJ5 →
Q5TM66 0.984 Q5TM66 →
Q8N1P7 0.982 Q8N1P7 →
Q7Z6P3 0.982 Q7Z6P3 →
A5D7J3 0.981 A5D7J3 →
Q1ED39 0.981 Q1ED39 →
Q767M0 0.981 Q767M0 →
P0C671 0.981 P0C671 →
Q5XFX8 0.980 Q5XFX8 →
Q7YR40 0.980 Q7YR40 →
Q6NYC8 0.979 Q6NYC8 →
MDC1 Mediator of DNA damage checkpoint protein 1 0.979 landscape →
Q9Y6A5 0.979 Q9Y6A5 →
Q8CB87 0.979 Q8CB87 →
Q9UDV7 0.979 Q9UDV7 →
Q8BQ30 0.979 Q8BQ30 →
Q8IYF1 0.979 Q8IYF1 →
Q5TM68 0.978 Q5TM68 →
B1ASB6 0.978 B1ASB6 →
A0A8I3PMN2 0.978 A0A8I3PMN2 →
Q9H7P9 0.978 Q9H7P9 →
Q7Z591 0.978 Q7Z591 →
Q58CQ0 0.978 Q58CQ0 →
Q96L96 0.978 Q96L96 →
Q86VY4 0.978 Q86VY4 →
Q9BUA3 0.978 Q9BUA3 →
Q3UNH4 0.977 Q3UNH4 →
Q9PU53 0.977 Q9PU53 →
Q96BT3 0.977 Q96BT3 →
NES Nestin 0.977 landscape →