Sugi Predict
/ Targets
/ POLR2B
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to POLR2B by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Baclofen for the Treatment of Alcohol Drinkers |
PHASE2/PHASE3 | COMPLETED |
| A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder |
PHASE3 | COMPLETED |
| Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration |
PHASE1/PHASE2 | RECRUITING |
| Subtenon Autologous Platelet-Rich Plasma in Inherited and Degenerative Retinal Diseases |
PHASE1/PHASE2 | ACTIVE_NOT_RECRUITING |
| Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer |
PHASE2 | UNKNOWN |
| A Study of Bezafibrate in Mitochondrial Myopathy |
PHASE2 | COMPLETED |
| PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS |
PHASE2 | COMPLETED |
| GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemia |
PHASE1 | COMPLETED |
| Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) |
nan | COMPLETED |
| Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases |
nan | UNKNOWN |
| InsightRP2 Registry |
nan | RECRUITING |
| S8814A Biomarkers in Predicting Outcome in Postmenopausal Women With Hormone Receptor-Positive, Node-Positive Breast Cancer Treated With Tamoxifen With or Without Cyclophosphamide, Doxorubicin, and Fluorouracil |
nan | COMPLETED |
| DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease |
nan | COMPLETED |
| Changes in DNA After Radiation Therapy in Patients With Prostate Cancer |
nan | COMPLETED |
| Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors |
nan | COMPLETED |
| A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients |
nan | COMPLETED |
| Biomarkers in Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without Rituximab |
nan | COMPLETED |
| S9031-S9126-S9333-S9500-B Biomarker Expression in Patients With Acute Myeloid Leukemia |
nan | COMPLETED |
| Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics |
nan | UNKNOWN |
| Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing |
nan | RECRUITING |
| Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam |
nan | UNKNOWN |
| Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission. |
nan | UNKNOWN |
| Study of Specimens From Young Patients With Neuroblastoma |
nan | COMPLETED |
| A Study of the Genetic Analysis of Brain Disorders |
nan | COMPLETED |
| Recombinant Interferon Alfa-2b in Treating Patients With Melanoma |
nan | COMPLETED |
| Identification and Characterization of Ovarian Cancer and Endometrial Cancer Specific Biomarkers in Vaginal Fluids |
nan | WITHDRAWN |
| Impact of Bariatric and Metabolic Surgery on the Reduction of Premature Aging. |
nan | COMPLETED |
| Prospective Open Clinical and Genetic Study of Patients With Retinitis Pigmentosa |
nan | COMPLETED |
| Genetic Investigation of Cancer Predisposition |
nan | NOT_YET_RECRUITING |
Related proteins — ESM-2 sequence neighbours (a POLR2B binder may also engage these)