Sugi Predict

Sugi Predict / Targets / PRPF19

PRPF19

Pre-mRNA-processing factor 19 · Q9UMS4 · PRPF19 on Sugi Atlas →

0 patent compounds predicted against PRPF19, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to PRPF19 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001 PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Personalized Antisense Oligonucleotide Therapy for a Single Participant With PRPH2 Mutation Associated With Retinal Dystrophy PHASE1/PHASE2ACTIVE_NOT_RECRUITING
MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby) PHASE1COMPLETED
SAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects PHASE1COMPLETED
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia PHASE1RECRUITING
Natural History of PRPF31 Mutation-Associated Retinal Dystrophy nanACTIVE_NOT_RECRUITING
Clinical and Genetic Findings in Patients With PRPF31-associated Retinitis Pigmentosa nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study) nanRECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Cancer in Inherited Bone Marrow Failure Syndromes nanRECRUITING
Genetic Investigation of Cancer Predisposition nanNOT_YET_RECRUITING
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Identification and Characterization of Novel Non-Coding Variants That Contribute to Genetic Disorders nanCOMPLETED
Identification of New FTLD Genes nanUNKNOWN
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
International PPB/DICER1 Registry nanRECRUITING
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia nanRECRUITING
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia nanRECRUITING
SRSF2 Gene Mutation in Patients With t-MDS/AML nanCOMPLETED
Natural History Study for Patients With Nemaline Myopathy in the UK nanACTIVE_NOT_RECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PRPF19 binder may also engage these)

ProteinNameSimilarity
Q08E38 — 1.000 Q08E38 →
Q9JMJ4 — 1.000 Q9JMJ4 →
Q5ZMA2 — 1.000 Q5ZMA2 →
Q99KP6 — 1.000 Q99KP6 →
Q10051 — 0.997 Q10051 →
B4P116 — 0.993 B4P116 →
Q9C1X1 — 0.993 Q9C1X1 →
Q6NNP0 — 0.993 Q6NNP0 →
Q5RKI0 — 0.990 Q5RKI0 →
O94365 — 0.990 O94365 →
WDR1 WD repeat-containing protein 1 0.990 landscape →
Q0VC24 — 0.989 Q0VC24 →
O60137 — 0.989 O60137 →
O22785 — 0.988 O22785 →
O14435 — 0.988 O14435 →
Q6DIF4 — 0.987 Q6DIF4 →
A1DFN6 — 0.986 A1DFN6 →
B8AP31 — 0.986 B8AP31 →
Q9ZU34 — 0.986 Q9ZU34 →
Q7K4B3 — 0.985 Q7K4B3 →
B4JPT9 — 0.985 B4JPT9 →
F1SS88 — 0.985 F1SS88 →
B3MET8 — 0.984 B3MET8 →
B4GT01 — 0.984 B4GT01 →
Q8L4J2 — 0.984 Q8L4J2 →
P20053 — 0.984 P20053 →
Q2KJH4 — 0.983 Q2KJH4 →
Q9C270 — 0.983 Q9C270 →
Q7QJ33 — 0.983 Q7QJ33 →
Q8VYZ5 — 0.983 Q8VYZ5 →