RABGGTB — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL10047259	1.00	9/20
SCHEMBL10047260	1.00	9/20
SCHEMBL10047265	1.00	9/20
SCHEMBL10073357	1.00	9/20
SCHEMBL10073361	1.00	9/20
SCHEMBL10073370	1.00	9/20
SCHEMBL10047253	0.85	9/20
SCHEMBL10073371	0.85	9/20
SCHEMBL10047245	0.84	9/20
SCHEMBL10072988	0.84	9/20
SCHEMBL14882801	0.84	9/20
SCHEMBL10047250	0.83	9/20
SCHEMBL10073599	0.83	9/20
SCHEMBL10047264	0.81	9/20
SCHEMBL10073606	0.81	9/20
SCHEMBL10047248	0.78	9/20
SCHEMBL10073812	0.78	9/20
SCHEMBL10047249	0.77	9/20
SCHEMBL10072993	0.77	9/20
SCHEMBL14882690	0.77	9/20

Clinical trials — most relevant to RABGGTB by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Gemcitabine Hydrochloride and Oxaliplatin or Observation in Treating Patients With Biliary Tract Cancer That Has Been Removed by Surgery	PHASE3	COMPLETED
NEO100 and High-Grade Meningioma	PHASE2	RECRUITING
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma	PHASE1/PHASE2	RECRUITING
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC)	PHASE2	COMPLETED
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer	PHASE2	COMPLETED
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC	PHASE2	COMPLETED
Study of the Mechanisms of Asthma	PHASE1	COMPLETED
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients	nan	RECRUITING
Longitudinal Observational Study of Severe Asthma	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Study of the Pathophysiological Mechanisms Involved in Bleeding Events	nan	COMPLETED
Tolerance in Beekeepers	nan	RECRUITING
Identifying Shared Genetic Susceptibility Regions in Chronic Beryllium Disease and Sarcoidosis	nan	COMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Clinical Application of PET Imaging Targeting GPA33 in Malignant Tumors	nan	NOT_YET_RECRUITING
Role of Polymorphisms in the IL-1 Gene Cluster	nan	COMPLETED
Chromosome 5Q Gene Variants and Asthma-Related Traits	nan	COMPLETED
Gene Expression in Inflammatory Bowel Disease	nan	ENROLLING_BY_INVITATION
Genetic Variants Associated With the Risk of Gall Stones and Cirrhosis.	nan	NOT_YET_RECRUITING
Severe Asthma Research Program - Wake Forest University	nan	COMPLETED
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Refractory Asthma Stratification Programme (RASP) Bronchoscopy Study	nan	UNKNOWN
Registry and Natural History of Epilepsy-Dyskinesia Syndromes	nan	RECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease	nan	UNKNOWN
Molecular Mechanism of Asthma	nan	WITHDRAWN
Autophagy Bladder Cancer	nan	UNKNOWN
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.	nan	ACTIVE_NOT_RECRUITING
Intravenous Terbutaline in Severe Status Asthmaticus	nan	UNKNOWN
Genetic Epidemiology of Asthma in Costa Rica	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RABGGTB binder may also engage these)

Protein	Name	Similarity
P53612	—	1.000	P53612 →
Q08603	—	1.000	Q08603 →
Q5E9B3	—	1.000	Q5E9B3 →
Q84J75	—	1.000	Q84J75 →
Q9LHL5	—	0.999	Q9LHL5 →
Q8BUY9	—	0.996	Q8BUY9 →
P41992	—	0.995	P41992 →
P53610	—	0.994	P53610 →
P20133	—	0.993	P20133 →
Q5EAD5	—	0.992	Q5EAD5 →
P46960	—	0.990	P46960 →
O93830	—	0.989	O93830 →
Q8K2I1	—	0.988	Q8K2I1 →
PGGT1B	Geranylgeranyl transferase type-1 subunit beta	0.986	landscape →
FNTB	Protein farnesyltransferase subunit beta	0.985	landscape →
P49355	—	0.985	P49355 →
B0G172	—	0.984	B0G172 →
Q02293	—	0.984	Q02293 →
Q04903	—	0.975	Q04903 →
Q55DA3	—	0.975	Q55DA3 →
O13782	—	0.973	O13782 →
P18898	—	0.972	P18898 →
P22007	—	0.972	P22007 →
O80642	—	0.971	O80642 →
Q4WES9	—	0.967	Q4WES9 →
A0A0E0SP71	—	0.967	A0A0E0SP71 →
A0A067FI21	—	0.964	A0A067FI21 →
Q96WJ0	—	0.964	Q96WJ0 →
Q10231	—	0.964	Q10231 →
P32434	—	0.964	P32434 →