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RAC2

Ras-related C3 botulinum toxin substrate 2 · P15153 · RAC2 on Sugi Atlas →

1,200 patent compounds predicted against RAC2, 789 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1461351 SCHEMBL1461351 1.00 1/20
Mbq-167 Mbq-167 (SCHEMBL19514489) 1.00 1/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL384979) 0.98 1/20
SCHEMBL1460422 SCHEMBL1460422 0.87 1/20
SCHEMBL19531601 SCHEMBL19531601 0.85 1/20
SCHEMBL1461760 SCHEMBL1461760 0.84 1/20
SCHEMBL1461794 SCHEMBL1461794 0.84 1/20
SCHEMBL1461829 SCHEMBL1461829 0.84 1/20
SCHEMBL4499457 SCHEMBL4499457 0.84 1/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL1461295) 0.83 1/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL1461390) 0.83 1/20
SCHEMBL19531596 SCHEMBL19531596 0.83 1/20
SCHEMBL19531598 SCHEMBL19531598 0.83 1/20
SCHEMBL20677953 SCHEMBL20677953 0.82 1/20
SCHEMBL19531619 SCHEMBL19531619 0.82 1/20
SCHEMBL19514500 SCHEMBL19514500 0.81 1/20
SCHEMBL19514602 SCHEMBL19514602 0.81 1/20
SCHEMBL1461466 SCHEMBL1461466 0.81 1/20
SCHEMBL4161227 SCHEMBL4161227 0.81 1/20
SCHEMBL19531592 SCHEMBL19531592 0.81 1/20

Clinical trials — most relevant to RAC2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 PHASE2COMPLETED
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 PHASE2COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Simvastatin in Secondary Progressive Multiple Sclerosis PHASE2COMPLETED
BIBW 2992 Plus Simvastatin vs. BIBW 2992 in Previously Treated Patients With Advanced Non-adenocarcinomatous NSCLC PHASE2COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Interleukin-2 Treatment for Wiskott-Aldrich Syndrome PHASE1COMPLETED
FAK Inhibitor in Patients With Advanced Solid Tumors PHASE1NOT_YET_RECRUITING
Responders to Rhythmic Auditory Cueing in Parkinson Disease PHASE1COMPLETED
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
ADRB3, ROCK2 and GEF Levels in Overactive Bladder Patients nanCOMPLETED
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
Evaluation of Vasopressin in the Vessels of Ovarian Neoplasms nanCOMPLETED
Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis nanCOMPLETED
Genetic Analysis of Familial Melanoma nanCOMPLETED
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Prevalence and Characterization of Pain in RASopathies nanUNKNOWN
Clinical Genetics Branch Eligibility Screening Survey nanNOT_YET_RECRUITING
The Roles of Neutrophil Elastase in Lung Cancer nanUNKNOWN
Gait in Rare Diseases nanCOMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
Genetic Identification (ID) of Segmental Dysplastic Nevi nanWITHDRAWN
Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2) nanCOMPLETED
Parkinson's Families Project nanRECRUITING
Family Myopia Study nanCOMPLETED
Biomarkers of CASH nanACTIVE_NOT_RECRUITING
Congenital Hemolytic and Dyserythropoietic Anemias nanRECRUITING
RASopathy Biorepository nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a RAC2 binder may also engage these)

ProteinNameSimilarity
Q9TU25 — 1.000 Q9TU25 →
Q05144 — 1.000 Q05144 →
O88931 — 1.000 O88931 →
P40792 — 1.000 P40792 →
P48554 — 0.999 P48554 →
RAC1 Ras-related C3 botulinum toxin substrate 1 0.997 landscape →
P62999 — 0.997 P62999 →
P60764 — 0.997 P60764 →
RAC3 Ras-related C3 botulinum toxin substrate 3 0.997 landscape →
Q6RUV5 — 0.996 Q6RUV5 →
A0A286QZ36 — 0.996 A0A286QZ36 →
P63001 — 0.996 P63001 →
Q03206 — 0.995 Q03206 →
P62998 — 0.995 P62998 →
CDC42 Cell division control protein 42 homolog 0.988 landscape →
P60766 — 0.988 P60766 →
P34145 — 0.988 P34145 →
P60952 — 0.988 P60952 →
Q05062 — 0.987 Q05062 →
Q8CFN2 — 0.985 Q8CFN2 →
Q007T2 — 0.985 Q007T2 →
Q2KJ93 — 0.985 Q2KJ93 →
C4YDI6 — 0.984 C4YDI6 →
Q9C3Y4 — 0.984 Q9C3Y4 →
Q16YG0 — 0.984 Q16YG0 →
Q29HY3 — 0.984 Q29HY3 →
Q90694 — 0.983 Q90694 →
Q22038 — 0.983 Q22038 →
Q4R4R6 — 0.983 Q4R4R6 →
Q17031 — 0.982 Q17031 →