RBBP7

Histone-binding protein RBBP7 · Q16576 · RBBP7 on Sugi Atlas →

4,688 patent compounds predicted against RBBP7, 3,756 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2591826 SCHEMBL2591826 0.66 6/20
Riboflavin Riboflavin (SCHEMBL7706) 1.00 4/20
Riboflavin Riboflavin (SCHEMBL7707) 1.00 4/20
SCHEMBL182061 SCHEMBL182061 1.00 4/20
SCHEMBL182062 SCHEMBL182062 1.00 4/20
Riboflavin Riboflavin (SCHEMBL297531) 1.00 4/20
Riboflavin Riboflavin (SCHEMBL341564) 1.00 4/20
Riboflavin Riboflavin (SCHEMBL2420598) 1.00 4/20
Riboflavin Riboflavin (SCHEMBL1983532) 0.98 4/20
Riboflavin Riboflavin (SCHEMBL246757) 0.96 4/20
Riboflavin Riboflavin (SCHEMBL1064647) 0.96 4/20
Riboflavin Riboflavin (SCHEMBL50096) 0.92 4/20
Riboflavin Riboflavin (SCHEMBL826819) 0.92 4/20
Riboflavin Riboflavin (SCHEMBL2127865) 0.92 4/20
Riboflavin Riboflavin (SCHEMBL2798981) 0.92 4/20
Riboflavin Riboflavin (SCHEMBL2799105) 0.92 4/20
Riboflavin Riboflavin (SCHEMBL2799109) 0.92 4/20
Riboflavin Riboflavin (SCHEMBL2799507) 0.92 4/20
SCHEMBL2595231 SCHEMBL2595231 0.91 4/20
Riboflavin Riboflavin (SCHEMBL2241200) 0.90 4/20

Clinical trials — most relevant to RBBP7 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt PHASE4COMPLETED
Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients PHASE3UNKNOWN
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma PHASE1/PHASE2COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Vorinostat in Children PHASE1/PHASE2COMPLETED
Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation PHASE2UNKNOWN
LBH589 Treatment for Refractory Clear Cell Renal Carcinoma PHASE2COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
IST Neoadjuvant Abraxane in Newly Diagnosed Breast Cancer PHASE2UNKNOWN
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
A Phase I Study of Systemic Gene Therapy With SGT-94 in Patients With Solid Tumors PHASE1COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma PHASE1UNKNOWN
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck PHASE1COMPLETED
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma EARLY_PHASE1RECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers nanUNKNOWN
CMOP Regimen and Chidamide in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma nanUNKNOWN
The Development of Human Papillomavirus Type 16 E7-Specific Human Immunologic Assays in Non-HLA2 Type Human Being nanUNKNOWN
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics nanCOMPLETED
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a RBBP7 binder may also engage these)

ProteinNameSimilarity
Q71UF4 1.000 Q71UF4 →
Q4R304 1.000 Q4R304 →
Q60973 1.000 Q60973 →
Q3SWX8 1.000 Q3SWX8 →
Q9I8G9 1.000 Q9I8G9 →
Q24572 1.000 Q24572 →
Q5R654 1.000 Q5R654 →
Q6P315 0.992 Q6P315 →
Q8AVH1 0.990 Q8AVH1 →
Q7ZTY4 0.988 Q7ZTY4 →
O93377 0.957 O93377 →
Q6P3H7 0.944 Q6P3H7 →
Q5M7K4 0.942 Q5M7K4 →
Q6INH0 0.938 Q6INH0 →
Q9W7I5 0.933 Q9W7I5 →
Q3MHL3 0.929 Q3MHL3 →
Q5RF92 0.928 Q5RF92 →
DCAF7 DDB1- and CUL4-associated factor 7 0.927 landscape →
RBBP4 Histone-binding protein RBBP4 0.923 landscape →
Q60972 0.923 Q60972 →
Q9BQ87 0.923 Q9BQ87 →
P61963 0.922 P61963 →
Q8BHJ5 0.915 Q8BHJ5 →
Q5RE95 0.915 Q5RE95 →
Q86VZ2 0.914 Q86VZ2 →
Q6GPC6 0.912 Q6GPC6 →
Q9V3J8 0.911 Q9V3J8 →
Q9QXE7 0.911 Q9QXE7 →
TBL1XR1 F-box-like/WD repeat-containing protein TBL1XR1 0.910 landscape →
Q4R8H1 0.910 Q4R8H1 →