RFTN1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to RFTN1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision	PHASE3	COMPLETED
Investigator-initiated Clinical Trial of MIKE-1	PHASE1/PHASE2	UNKNOWN
Hereditary Sensory Neuropathy Serine Trial	PHASE2	UNKNOWN
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)	PHASE1/PHASE2	RECRUITING
Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa	PHASE1	COMPLETED
Familial Partial Lipodystrophy Study	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Immune Cell Response to Stimuli	nan	RECRUITING
Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)	nan	WITHDRAWN
Assessing Colonic Folate Absorption & Metabolism	nan	UNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Studies on the Expression and Functions of RLIP76 in Blood Samples of Healthy Human Subjects	nan	WITHDRAWN
Molecular Analysis of Patients With Neuromuscular Disease	nan	RECRUITING
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models	nan	COMPLETED
Genetic Analysis of Fraser Syndrome and Fryns Syndrome	nan	COMPLETED
Family Myopia Study	nan	COMPLETED
Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial	nan	COMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan	nan	ENROLLING_BY_INVITATION
Lipodystrophy Connect Patient Registry	nan	COMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others	nan	RECRUITING
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance	nan	COMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)	nan	RECRUITING
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization	nan	COMPLETED
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome	nan	ACTIVE_NOT_RECRUITING
Molecular Genetics of Retinal Degenerations	nan	COMPLETED
Application of Linkage Analysis in the Identification of Novel Hereditary Factors in Familial Aneurysms	nan	ACTIVE_NOT_RECRUITING
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome)	nan	COMPLETED
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With Classic Polycystic Ovary Syndrome (PCOS)	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a RFTN1 binder may also engage these)

Protein	Name	Similarity
Q6A0D4	—	1.000	Q6A0D4 →
Q7SZI5	—	0.998	Q7SZI5 →
Q2PFD7	—	0.995	Q2PFD7 →
Q5R458	—	0.995	Q5R458 →
Q9NYI0	—	0.994	Q9NYI0 →
RNF213	E3 ubiquitin-protein ligase RNF213	0.993	landscape →
Q9CXB8	—	0.993	Q9CXB8 →
E9Q555	—	0.993	E9Q555 →
Q5XG73	—	0.992	Q5XG73 →
A2AHC3	—	0.992	A2AHC3 →
Q9Z2U2	—	0.992	Q9Z2U2 →
Q76I79	—	0.992	Q76I79 →
Q5DW34	—	0.992	Q5DW34 →
Q9BQK8	—	0.992	Q9BQK8 →
Q8C0C0	—	0.992	Q8C0C0 →
A6QP06	—	0.992	A6QP06 →
Q640U0	—	0.992	Q640U0 →
A6H5Y1	—	0.992	A6H5Y1 →
Q8BL06	—	0.992	Q8BL06 →
Q66H04	—	0.991	Q66H04 →
Q52LD8	—	0.991	Q52LD8 →
Q96QP1	—	0.991	Q96QP1 →
Q76N89	—	0.991	Q76N89 →
KDM3B	Lysine-specific demethylase 3B	0.990	landscape →
Q6DFV7	—	0.990	Q6DFV7 →
Q28DE6	—	0.990	Q28DE6 →
A3KMW7	—	0.990	A3KMW7 →
Q0VET5	—	0.990	Q0VET5 →
Q8CHX7	—	0.990	Q8CHX7 →
Q8C636	—	0.990	Q8C636 →