RPAP1

RNA polymerase II-associated protein 1 · Q9BWH6 · RPAP1 on Sugi Atlas →

0 patent compounds predicted against RPAP1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to RPAP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) PHASE2RECRUITING
S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
Peptide Vaccine Focusing on Prevention of the Recurrence for Bladder Cancer PHASE2UNKNOWN
A Study of Cediranib and Olaparib at the Time Ovarian Cancer Worsens on Olaparib PHASE2COMPLETED
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers PHASE1/PHASE2COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
Safety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and Lymphomas PHASE1COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers PHASE1RECRUITING
AZD2281 and Cisplatin Plus Gemcitabine to Treat Solid Tumor Cancers PHASE1COMPLETED
Novel Peptide Vaccination for Patients With Advanced Bladder Cancer PHASE1COMPLETED
ABT-888 Plus Metronomic Cyclophosphamide to Treat Cancer PHASE1COMPLETED
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors PHASE1COMPLETED
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors PHASE1ACTIVE_NOT_RECRUITING
PET Imaging of PARP Activity in Cancer EARLY_PHASE1UNKNOWN
Chromosomal Translocations in Chandigarh Police nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Study of the Effect of Innate on the Inflammatory Response to Endotoxin nanRECRUITING
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) nanCOMPLETED
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Telomere Repair Gene Mutation in Inflammatory Bowel Disease nanCOMPLETED
Efficacy and Adverse Effects of Olaparib in Ovarian Cancer. nanUNKNOWN
Telomeres Length in Israeli Fibrotic ILD Patients nanENROLLING_BY_INVITATION
Studying Tissue Samples From Patients With Stage II Colon Cancer Treated on Clinical Trial CLB-9581 nanCOMPLETED
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RPAP1 binder may also engage these)

ProteinNameSimilarity
Q3T1I9 1.000 Q3T1I9 →
A0JN53 1.000 A0JN53 →
Q80TE0 0.997 Q80TE0 →
Q8VDP4 0.988 Q8VDP4 →
Q6ZQA0 0.986 Q6ZQA0 →
O43299 0.986 O43299 →
Q9JL70 0.986 Q9JL70 →
TELO2 Telomere length regulation protein TEL2 homolog 0.984 landscape →
O75064 0.984 O75064 →
O75800 0.984 O75800 →
Q6PDZ2 0.983 Q6PDZ2 →
Q9DC40 0.983 Q9DC40 →
Q9WV70 0.983 Q9WV70 →
Q5R8S0 0.983 Q5R8S0 →
Q5T124 0.983 Q5T124 →
Q15572 0.983 Q15572 →
Q8C3S2 0.983 Q8C3S2 →
Q08CY4 0.982 Q08CY4 →
Q9EQR6 0.982 Q9EQR6 →
Q9H7M6 0.982 Q9H7M6 →
Q66K74 0.982 Q66K74 →
P86182 0.982 P86182 →
D3ZND0 0.982 D3ZND0 →
Q562E7 0.982 Q562E7 →
D3ZVB0 0.982 D3ZVB0 →
Q9Z136 0.982 Q9Z136 →
CCDC22 Coiled-coil domain-containing protein 22 0.982 landscape →
P58660 0.982 P58660 →
Q6GPP1 0.982 Q6GPP1 →
Q66H85 0.982 Q66H85 →