RPL7A — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL31246618	0.65	15/20
SCHEMBL24176574	1.00	14/20
SCHEMBL29596176	1.00	14/20
SCHEMBL31246964	1.00	14/20
SCHEMBL31247233	0.73	14/20
SCHEMBL31246552	0.63	14/20
SCHEMBL31227441	0.62	14/20
SCHEMBL31247182	0.61	14/20
SCHEMBL31227395	0.60	14/20
SCHEMBL31246768	0.59	14/20
SCHEMBL31246904	0.59	14/20
SCHEMBL31246869	0.58	14/20
SCHEMBL31247201	0.58	14/20
SCHEMBL31227052	0.55	14/20
SCHEMBL31246799	0.55	14/20
SCHEMBL31246750	0.55	14/20
SCHEMBL31247111	0.55	14/20
SCHEMBL31246571	0.55	14/20
SCHEMBL31247006	0.51	14/20
SCHEMBL31227365	0.50	14/20

Clinical trials — most relevant to RPL7A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients	PHASE1/PHASE2	COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS	PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors	PHASE1	COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors	PHASE1	COMPLETED
Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment	PHASE1	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
RibOSE - Glucose and Resistance Exercise Training	nan	COMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)	nan	COMPLETED
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)	nan	RECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Lumbar Spine Muscle Degeneration Inhibits Rehabilitation-Induced Muscle Recovery	nan	COMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a RPL7A binder may also engage these)

Protein	Name	Similarity
Q4R5C2	—	1.000	Q4R5C2 →
P62425	—	1.000	P62425 →
P12970	—	1.000	P12970 →
Q2TBQ5	—	1.000	Q2TBQ5 →
P32429	—	1.000	P32429 →
O57592	—	1.000	O57592 →
Q90YW2	—	1.000	Q90YW2 →
O13672	—	1.000	O13672 →
P0DJ14	—	1.000	P0DJ14 →
P49692	—	0.999	P49692 →
Q966C6	—	0.999	Q966C6 →
O76732	—	0.998	O76732 →
Q5ANA1	—	0.998	Q5ANA1 →
A0A1D8PF11	—	0.998	A0A1D8PF11 →
P46223	—	0.998	P46223 →
P29453	—	0.997	P29453 →
P35685	—	0.995	P35685 →
Q9LZH9	—	0.994	Q9LZH9 →
P17076	—	0.993	P17076 →
P0DKK7	—	0.992	P0DKK7 →
Q54ZD1	—	0.990	Q54ZD1 →
Q8SSG1	—	0.984	Q8SSG1 →
O65353	—	0.981	O65353 →
G1STW0	—	0.980	G1STW0 →
Q58DW5	—	0.979	Q58DW5 →
B5X171	—	0.979	B5X171 →
Q29375	—	0.979	Q29375 →
P05737	—	0.978	P05737 →
Q7TND5	—	0.978	Q7TND5 →
A0CEY2	—	0.978	A0CEY2 →