SAMHD1

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 · Q9Y3Z3 · SAMHD1 on Sugi Atlas →

0 patent compounds predicted against SAMHD1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SAMHD1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Simplification to Atazanavir/Ritonavir + Lamivudine as Maintenance Therapy PHASE4COMPLETED
Alternative Dosing Strategy for Anti-HIV Drugs PHASE4COMPLETED
A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection PHASE3UNKNOWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve) PHASE3WITHDRAWN
Targeting de Novo Pyrimidine Biosynthesis by Leflunomide for the Treatment of COVID-19 Virus Disease PHASE3COMPLETED
Acelarin First Line Randomised Pancreatic Study PHASE2/PHASE3SUSPENDED
Evaluation of Compliance With Treatment by Genvoya in HIV Post-exposure Prophylaxis PHASE3COMPLETED
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia PHASE1/PHASE2COMPLETED
A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers PHASE2COMPLETED
Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome PHASE2COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Study of Cytolytic Viral Activation Therapy (CVAT) for Recurrent/Metastatic Nasopharyngeal Carcinoma PHASE1UNKNOWN
Comparison of Concentration-time Course of Plasma and Intracellular Raltegravir in Healthy Volunteers PHASE1COMPLETED
The Safety and Effectiveness of BI-RG-587 in HIV-Infected Patients PHASE1COMPLETED
PRO#0118: Decitabine Plus Mini Flu-Bu PHASE1COMPLETED
Nucleoside Therapy in Patients With Telomere Biology Disorders PHASE1RECRUITING
Clinical Trial to Evaluate Drug-drug Interactions Between Darunavir/Cobicistat and Etravirine in Hiv- Infected Patients PHASE1COMPLETED
Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer PHASE1ACTIVE_NOT_RECRUITING
A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children With HIV Infection PHASE1COMPLETED
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors PHASE1COMPLETED
Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E nanUNKNOWN
A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors nanWITHDRAWN
Role and Interactions of Adenosine, Receptors, Methionine Cycle Nutritional, Metabolic and Genetic Determinants in the Onset of Atrial Fibrillation in Normal Heart nanUNKNOWN
Prevalence of Adenosine Deaminase (ADA) Enzyme Deficiency Disease in Adult Patients With Pulmonary Alveolar Proteinosis nanUNKNOWN
Observational Study Evaluating the Prevalence of Enzyme Deficiency in Pulmonology Clinics (ADA) nanUNKNOWN
Thymidine Kinase 1 in Risk Assessment for Hereditary Breast /Ovarian Cancer nanUNKNOWN
Accelerated Aging, HIV Infection, Antiretroviral Therapies nanCOMPLETED
Clinical Genetics Branch Eligibility Screening Survey nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SAMHD1 binder may also engage these)

ProteinNameSimilarity
Q502K2 1.000 Q502K2 →
Q60710 1.000 Q60710 →
Q0VCA5 0.999 Q0VCA5 →
Q6INN8 0.997 Q6INN8 →
Q5ZJL9 0.993 Q5ZJL9 →
B0G107 0.978 B0G107 →
Q8BJ37 0.978 Q8BJ37 →
Q9TTH8 0.976 Q9TTH8 →
Q2TV84 0.976 Q2TV84 →
P20807 0.976 P20807 →
Q64691 0.975 Q64691 →
Q803R5 0.975 Q803R5 →
P16259 0.974 P16259 →
Q1MTD3 0.974 Q1MTD3 →
Q5RAZ4 0.974 Q5RAZ4 →
Q2WEA5 0.973 Q2WEA5 →
Q9GLG7 0.973 Q9GLG7 →
Q7Z4N2 0.973 Q7Z4N2 →
Q5ZJM3 0.973 Q5ZJM3 →
Q58D72 0.973 Q58D72 →
Q5TYS0 0.973 Q5TYS0 →
A8DYE2 0.973 A8DYE2 →
P43368 0.973 P43368 →
B4NBB0 0.973 B4NBB0 →
Q9I8S2 0.972 Q9I8S2 →
Q6PA06 0.972 Q6PA06 →
Q6NUA1 0.972 Q6NUA1 →
B0XDC4 0.972 B0XDC4 →
A0A0G2K344 0.972 A0A0G2K344 →
O88509 0.972 O88509 →