SAV1

Protein salvador homolog 1 · Q9H4B6 · SAV1 on Sugi Atlas →

0 patent compounds predicted against SAV1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SAV1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Cornelia De Lange Syndrome: Assessing Positive Effects of Lithium Treatment PHASE2/PHASE3RECRUITING
Signal TrAnsduction Pathway Activity Analysis in OVarian cancER PHASE2/PHASE3RECRUITING
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer PHASE2COMPLETED
SCARFREE-001: Verteporfin for Scar Prevention PHASE2NOT_YET_RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes PHASE2COMPLETED
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
LY3022855 With BRAF/MEK Inhibition in Patients With Melanoma PHASE1/PHASE2COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Phase I Study of SC-43 Oral Solution in Subjects With Refractory Solid Tumors PHASE1WITHDRAWN
Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors PHASE1RECRUITING
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers PHASE1COMPLETED
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Hematological Anomalies in Children With Rasopathy nanRECRUITING
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Clinical Genetics Branch Eligibility Screening Survey nanNOT_YET_RECRUITING
Circulating Cell-free DNA-based Epigenetic Biomarker mSEPT9 for Hepatocellular Carcinoma Detection in Cirrhosis nanCOMPLETED
Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk Individuals nanRECRUITING
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia nanRECRUITING
NGS in Gallbladder Cancer and Response to Treatment nanRECRUITING
Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SAV1 binder may also engage these)

ProteinNameSimilarity
Q8VEB2 1.000 Q8VEB2 →
A4V8B4 1.000 A4V8B4 →
Q6E3D4 0.995 Q6E3D4 →
A2RUV4 0.995 A2RUV4 →
O62090 0.995 O62090 →
P97868 0.994 P97868 →
P27715 0.993 P27715 →
G5EC32 0.993 G5EC32 →
Q17353 0.993 Q17353 →
Q03345 0.993 Q03345 →
Q5HZJ0 0.992 Q5HZJ0 →
Q9R1Z8 0.992 Q9R1Z8 →
Q15154 0.992 Q15154 →
A8XU52 0.992 A8XU52 →
Q09801 0.992 Q09801 →
Q7ZXH3 0.992 Q7ZXH3 →
Q9NRR4 0.992 Q9NRR4 →
Q6FK59 0.992 Q6FK59 →
P28220 0.992 P28220 →
Q27IV2 0.992 Q27IV2 →
Q8STF6 0.992 Q8STF6 →
Q6DFG0 0.992 Q6DFG0 →
G5EEC5 0.992 G5EEC5 →
Q9XVN3 0.992 Q9XVN3 →
B4HEJ6 0.992 B4HEJ6 →
Q71M21 0.991 Q71M21 →
A0A1L8HFX9 0.991 A0A1L8HFX9 →
Q09350 0.991 Q09350 →
G5EEK3 0.991 G5EEK3 →
Q96SK2 0.991 Q96SK2 →