SCLY — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SCLY by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Selenium Supplementation in Youths With Autoimmune Thyroiditis	PHASE4	COMPLETED
The Effect of Q10 and Selen Supplement on Muscular Adverse Events in Statin Therapy	PHASE4	COMPLETED
Comparative Study of Dietary and Immunological Management of Refractory Epilepsy in Children	PHASE4	UNKNOWN
Trial of Supplementation With Aged Garlic Extract to Improve Endothelial Function in Patients With Metabolic Syndrome	PHASE4	UNKNOWN
Effects of High-dose Intravenous Selenium (Selenase®) in Adult Patients Subjected to Elective All-cause Heart Surgery	PHASE3	COMPLETED
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept	PHASE3	COMPLETED
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism	PHASE2	ACTIVE_NOT_RECRUITING
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients	PHASE2	WITHDRAWN
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels	PHASE1	COMPLETED
Characterization of the Pharmacokinetics of Oral Selenium Compounds in Humans Before and Following Supplementation	nan	COMPLETED
Selenium Levels in Patients With Abdominal Aneurysm	nan	ACTIVE_NOT_RECRUITING
Selenium and Immune Function	nan	COMPLETED
Thiol/Disulphide Homeostasis in Unexplained Infertility	nan	COMPLETED
Optimization of Selenoprotein P in Chinese Subjects	nan	COMPLETED
Selenium Supplementation of Patients With Cirrhosis	nan	COMPLETED
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione	nan	COMPLETED
External Nitric Oxide Measurement Through SNO Degradation	nan	ENROLLING_BY_INVITATION
The Natural History of Patients With Mutations in SEPN1 (SELENON) or LAMA2	nan	COMPLETED
Selenoprotein P and Non-alcoholic Fatty Liver Disease	nan	COMPLETED
Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers	nan	COMPLETED
Macrophage Migration Inhibitory Factor (MIF)- Cardiac Surgery	nan	COMPLETED
Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome	nan	UNKNOWN
Evaluation of Mitochondrial Enzyme Activity in Cesarean Section Patients	nan	UNKNOWN
Role of Vitamin C Infusion in Postoperative Mechanically Ventilated Neonates With Sepsis	nan	COMPLETED
Dietary Effects of Sulfur Amino Acids	nan	COMPLETED
Predicting Dietary Selenium Needs to Achieve Target Blood Selenium Levels	nan	COMPLETED
Sodium Selenite Supplementation in Patients With Head and Neck Cancer	nan	UNKNOWN
High-selenium Lentils Versus Arsenic Toxicity	nan	COMPLETED
Plant-based Diets and Body Weight and Selected Metabolic Parameters Management in Obese Patients.	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SCLY binder may also engage these)

Protein	Name	Similarity
Q68FT9	—	0.997	Q68FT9 →
A2VDS1	—	0.996	A2VDS1 →
Q9JLI6	—	0.992	Q9JLI6 →
Q5U4Q9	—	0.980	Q5U4Q9 →
Q66IQ6	—	0.977	Q66IQ6 →
P0DN31	—	0.974	P0DN31 →
W1QJK0	—	0.967	W1QJK0 →
Q99P39	—	0.967	Q99P39 →
O60028	—	0.967	O60028 →
O74351	—	0.966	O74351 →
B0YLW6	—	0.965	B0YLW6 →
O75600	—	0.964	O75600 →
O49543	—	0.963	O49543 →
P25374	—	0.963	P25374 →
Q9Z1J3	—	0.963	Q9Z1J3 →
Q0P5L8	—	0.962	Q0P5L8 →
P87187	—	0.960	P87187 →
Q61753	—	0.959	Q61753 →
Q9VKD3	—	0.959	Q9VKD3 →
P87185	—	0.958	P87185 →
Q6PG34	—	0.958	Q6PG34 →
P33280	—	0.958	P33280 →
A5GFY8	—	0.957	A5GFY8 →
Q60HD7	—	0.956	Q60HD7 →
Q5EAD2	—	0.956	Q5EAD2 →
Q8SQS2	—	0.956	Q8SQS2 →
PHGDH	D-3-phosphoglycerate dehydrogenase	0.956	landscape →
Q1H361	—	0.956	Q1H361 →
O08651	—	0.956	O08651 →
Q8IW45	—	0.956	Q8IW45 →