SDC1

Syndecan-1 · P18827 · SDC1 on Sugi Atlas →

0 patent compounds predicted against SDC1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SDC1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Dexmedetomidine to Prevent Hepatic Ischemia-reperfusion Injury-induced Glycocalyx Degradation and Early Allograft Dysfunction in Liver Transplantation PHASE4ACTIVE_NOT_RECRUITING
Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related Biomarkers PHASE4COMPLETED
Volume Kinetics for Hyperoncotic Albumin in Burn Patients as Well as for Healthy Subjects PHASE4COMPLETED
Study of Protection And Repair of Endothelial-glycocalyx in Sepsis (SPARES) PHASE2NOT_YET_RECRUITING
Clinical Trial of SBRT and Systemic Pembrolizumab With or Without Avelumab/Ipilimumab+ Dendritic Cells in Solid Tumors PHASE2UNKNOWN
Pilot Study Using Changes in Serum BCMA to Determine Disease Progression in Multiple Myeloma EARLY_PHASE1RECRUITING
Evaluation of Endothelial Glycocalyx in the Surgical Resuscitation of Major Burn Patients nanRECRUITING
Syndecan-1 a Surrogate Marker for IBD nanCOMPLETED
Early Diagnosis and Prognosis of Postoperative Sepsis by Presepsin and Syndecan-1 nanUNKNOWN
Impact of Perioperative Shedding of the Endothelial Glycocalyx on the Incidence of Postoperative Acute Kidney Injury in Patients Undergoing Valvular Heart Surgery. nanCOMPLETED
Albumin, COP and Endothelial Damage in Patients With ESLD Undergoing OLT nanCOMPLETED
VASCULUX-examination of the Pulmonary VASCUlar Barrier in Patients During LUng Transplantation nanUNKNOWN
Syndecan-4 as a Biomarker in Patients With Chagas Disease nanCOMPLETED
The Glycocalyx in COVID-19 Patients. A Pilot Study nanCOMPLETED
Myoglobin Removal With CytoSorb in Rhabdomyolysis nanCOMPLETED
Perioperative Plasma Levels of Glycocalyx Markers in Colon Surgery. nanUNKNOWN
Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer Patient nanRECRUITING
Evaluation of Damaging Factors to Endothelial Glycocalyx During Heart Surgery. nanCOMPLETED
COronary Microcirculation and Troponin Elevation in Septic Shock nanCOMPLETED
Alpha-lipoic Acid in Critically Ill Patients With Sepsis nanCOMPLETED
The Effect of Anesthetics Agents on Vascular Injury and Level of Syndecan-1 During Knee Surgery nanCOMPLETED
Comparison of Liberal and Restrictive Fluid Management on the Endothelial Glycocalyx in Radical Cystectomy nanCOMPLETED
Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy nanACTIVE_NOT_RECRUITING
Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho) nanRECRUITING
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches nanUNKNOWN
Randomized Trial of Fresh Frozen Plasma Versus Albumin in Acute Burn Resuscitation nanCOMPLETED
Impact of Perioperative Shedding of the Endothelial Glycocalyx on Short-term Postoperative Complication in Patients Undergoing Robot-assisted Esophagectomy nanCOMPLETED
Comparison of the Effects of Sevoflurane and Desflurane on Endothelial Glycocalyx nanCOMPLETED
Cardiogenic Shock Integrated PHenotyping for Event Reduction nanRECRUITING
Clinically Actionable Tumor-Associated Antigens in Prostate Cancer nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a SDC1 binder may also engage these)

ProteinNameSimilarity
Q08DZ5 1.000 Q08DZ5 →
P26260 1.000 P26260 →
P34740 1.000 P34740 →
P18828 0.996 P18828 →
P47951 0.996 P47951 →
Q64519 0.993 Q64519 →
P33671 0.991 P33671 →
Q9ERQ6 0.990 Q9ERQ6 →
O75056 0.989 O75056 →
Q52S86 0.989 Q52S86 →
O35188 0.989 O35188 →
P97808 0.988 P97808 →
P06484 0.988 P06484 →
Q71M36 0.988 Q71M36 →
P34900 0.987 P34900 →
P78423 0.987 P78423 →
Q9DF69 0.987 Q9DF69 →
Q28645 0.987 Q28645 →
O95196 0.986 O95196 →
Q8BHE4 0.986 Q8BHE4 →
Q9R0M4 0.986 Q9R0M4 →
Q8JZQ0 0.986 Q8JZQ0 →
O55145 0.985 O55145 →
P26261 0.985 P26261 →
Q9GKE2 0.985 Q9GKE2 →
Q1ECS6 0.984 Q1ECS6 →
Q95152 0.984 Q95152 →
O00592 0.984 O00592 →
Q96DB9 0.984 Q96DB9 →
P43407 0.984 P43407 →