SEC61A1

Protein transport protein Sec61 subunit alpha isoform 1 · P61619 · SEC61A1 on Sugi Atlas →

0 patent compounds predicted against SEC61A1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SEC61A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Targeting Endoplasmic Reticulum Stress in Human Hypertension PHASE1/PHASE2RECRUITING
Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy PHASE2COMPLETED
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops PHASE2UNKNOWN
Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers PHASE1/PHASE2RECRUITING
NEO100 and High-Grade Meningioma PHASE2RECRUITING
A Phase 2 Trial of SCO-101 in Combination With FOLFIRI for Patients With Metastatic Colorectal Cancer (mCRC) With Acquired Resistance to FOLFIRI PHASE1/PHASE2UNKNOWN
Modulate Cellular Stress in the Immune Cells to Reduce Rate of Symptomatic Viral Infection PHASE2COMPLETED
Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients PHASE1UNKNOWN
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors PHASE1COMPLETED
A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors PHASE1COMPLETED
Safety and Pharmacology Study of SNX-5422 in Subjects With Resistant Lung Adenocarcinoma PHASE1COMPLETED
HS-201, an HSP90 Inhibitor-linked Verteporfin for Detection of Solid Malignancies PHASE1WITHDRAWN
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors PHASE1COMPLETED
A Phase I Study of Pyrimethamine in Patients With GM2 Gangliosidosis PHASE1WITHDRAWN
PBA Use for Treatment of ATF6-/- Patients EARLY_PHASE1SUSPENDED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Quantification of GADD34 Expression in RA nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Study of Constitutional Platelet Disease nanUNKNOWN
Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children nanCOMPLETED
The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients nanRECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment. nanACTIVE_NOT_RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
Sj-subway, a Predictor for the Recurrence of High-risk Hormone Receptor-positive Breast That is Sensitive to Extended Endocrine Therapy nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Fatty Acids Lipidome and Oxidative Stress in Liver Transplantation nanUNKNOWN
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a SEC61A1 binder may also engage these)

ProteinNameSimilarity
Q90ZM2 1.000 Q90ZM2 →
Q9H9S3 1.000 Q9H9S3 →
P61621 1.000 P61621 →
P38377 1.000 P38377 →
Q5EA68 1.000 Q5EA68 →
Q98SN9 1.000 Q98SN9 →
Q98SN8 1.000 Q98SN8 →
Q5NVM7 1.000 Q5NVM7 →
Q7T278 1.000 Q7T278 →
Q9JLR1 1.000 Q9JLR1 →
Q8AY32 1.000 Q8AY32 →
Q7T277 1.000 Q7T277 →
Q90YL4 1.000 Q90YL4 →
Q8AY34 1.000 Q8AY34 →
Q5R5L5 1.000 Q5R5L5 →
Q54XK2 1.000 Q54XK2 →
Q8AY36 1.000 Q8AY36 →
Q8AY33 1.000 Q8AY33 →
Q870W0 1.000 Q870W0 →
Q6BN08 1.000 Q6BN08 →
Q8AY35 1.000 Q8AY35 →
Q8AY31 1.000 Q8AY31 →
P79088 1.000 P79088 →
P28541 1.000 P28541 →
Q96TW8 1.000 Q96TW8 →
P61620 1.000 P61620 →
P32915 0.999 P32915 →
Q2KHX4 0.999 Q2KHX4 →
Q9P8E3 0.998 Q9P8E3 →
O26134 0.998 O26134 →