Sugi Predict

Sugi Predict / Targets / SF3A3

SF3A3

Splicing factor 3A subunit 3 · Q12874 · SF3A3 on Sugi Atlas →

0 patent compounds predicted against SF3A3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SF3A3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy PHASE3UNKNOWN
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4 PHASE3ACTIVE_NOT_RECRUITING
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer PHASE1/PHASE2ACTIVE_NOT_RECRUITING
CpG-STAT3 siRNA CAS3/SS3 and Localized Radiation Therapy for the Treatment of Relapsed/Refractory B-Cell NHL PHASE1WITHDRAWN
A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Efficacy of SRP-9003 in Non-Ambulatory and Ambulatory Participants With Limb Girdle Muscular Dystrophy, Type 2E/R4 (Beta-Sarcoglycan [β-SG] Deficiency) PHASE1ACTIVE_NOT_RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care nanCOMPLETED
Molecular Disease Profile of Hematological Malignancies nanUNKNOWN
SRSF2 Gene Mutation in Patients With t-MDS/AML nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Clinical Study of Spinal Muscular Atrophy nanCOMPLETED
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping nanUNKNOWN
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients nanACTIVE_NOT_RECRUITING
Monitoring Mutational Burden in Low Risk MDS Patients Using Sequential Peripheral Blood Samples nanRECRUITING
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing nanRECRUITING
Genomic Services Research Program nanRECRUITING
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia nanRECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Studying Gene Expression in Tissue Samples From Young Patients With Acute Myeloid Leukemia nanCOMPLETED
Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS) nanRECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SF3A3 binder may also engage these)

ProteinNameSimilarity
Q9D554 — 1.000 Q9D554 →
Q9FG01 — 1.000 Q9FG01 →
O46106 — 1.000 O46106 →
O59706 — 0.994 O59706 →
P19736 — 0.992 P19736 →
Q966L5 — 0.990 Q966L5 →
O02328 — 0.989 O02328 →
Q9U2Y2 — 0.988 Q9U2Y2 →
A8XEG9 — 0.988 A8XEG9 →
B5X171 — 0.988 B5X171 →
P0CR72 — 0.988 P0CR72 →
F4IH25 — 0.987 F4IH25 →
Q9EQ61 — 0.987 Q9EQ61 →
P0CR73 — 0.987 P0CR73 →
O74977 — 0.987 O74977 →
Q8WTJ4 — 0.987 Q8WTJ4 →
Q751U1 — 0.987 Q751U1 →
Q7XVN7 — 0.987 Q7XVN7 →
A2WKK5 — 0.987 A2WKK5 →
A3LXF0 — 0.987 A3LXF0 →
Q24314 — 0.987 Q24314 →
Q19555 — 0.987 Q19555 →
Q6DEV3 — 0.987 Q6DEV3 →
Q09867 — 0.987 Q09867 →
P91136 — 0.986 P91136 →
P38344 — 0.986 P38344 →
Q3MNT0 — 0.986 Q3MNT0 →
O74925 — 0.986 O74925 →
Q4WWH6 — 0.986 Q4WWH6 →
Q21037 — 0.986 Q21037 →