SF3B5

Splicing factor 3B subunit 5 · Q9BWJ5 · SF3B5 on Sugi Atlas →

0 patent compounds predicted against SF3B5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SF3B5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Valproate and Levocarnitine in Children With Spinal Muscular Atrophy PHASE3UNKNOWN
Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS) PHASE1/PHASE2SUSPENDED
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia PHASE2RECRUITING
Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer PHASE2COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care nanCOMPLETED
SRSF2 Gene Mutation in Patients With t-MDS/AML nanCOMPLETED
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Molecular Disease Profile of Hematological Malignancies nanUNKNOWN
Monitoring Mutational Burden in Low Risk MDS Patients Using Sequential Peripheral Blood Samples nanRECRUITING
Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping nanUNKNOWN
GENOMED4ALL: Improving MDS Classification and Prognosis by AI nanUNKNOWN
Efficacy and Safety Study of EGCG/Tocotrienol in 18 Patients With Splicing-mutation-mediated Cystic Fibrosis (CF) nanCOMPLETED
Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS) nanRECRUITING
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer nanCOMPLETED
Clinical Study of Spinal Muscular Atrophy nanCOMPLETED
Mesenchymal Stem Cells in NPM1 Mutated Low Risk Acute Myeloid Leukemia: a Study of the Tumor Microenvironment and Its Contribution to the Outcome nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Mechanisms of Cell Death in Spinal Muscular Atrophy nanCOMPLETED
Prospective Study of Molecular Predictors of Survival in Myelodysplastic Syndromes nanCOMPLETED
Outcome Measures and Biomarkers in a Cohort of Spinal Muscular Atrophy Type III/ IV Patients nanACTIVE_NOT_RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Prognostic Molecular Markers in Patients With Myelodysplastic Syndrome nanCOMPLETED
Genomic Services Research Program nanRECRUITING
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SF3B5 binder may also engage these)

ProteinNameSimilarity
Q56K13 1.000 Q56K13 →
Q923D4 1.000 Q923D4 →
Q07934 1.000 Q07934 →
Q9VHI4 1.000 Q9VHI4 →
O68946 1.000 O68946 →
O68940 1.000 O68940 →
O29734 1.000 O29734 →
A8FE93 1.000 A8FE93 →
O10355 1.000 O10355 →
Q05268 0.999 Q05268 →
P58728 0.999 P58728 →
P12601 0.999 P12601 →
Q37870 0.999 Q37870 →
Q9MUR1 0.999 Q9MUR1 →
A9BD03 0.999 A9BD03 →
Q25330 0.999 Q25330 →
Q05142 0.999 Q05142 →
B4SVW1 0.999 B4SVW1 →
P74352 0.998 P74352 →
Q95748 0.998 Q95748 →
Q49Z67 0.998 Q49Z67 →
P08346 0.998 P08346 →
P44078 0.998 P44078 →
Q9QBY9 0.998 Q9QBY9 →
P84786 0.998 P84786 →
Q46244 0.998 Q46244 →
Q09526 0.998 Q09526 →
P08274 0.998 P08274 →
P0C2D4 0.998 P0C2D4 →
Q2YDG2 0.998 Q2YDG2 →