SFXN1

Sideroflexin-1 · Q9H9B4 · SFXN1 on Sugi Atlas →

0 patent compounds predicted against SFXN1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SFXN1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies PHASE4COMPLETED
Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept PHASE3COMPLETED
Safety and Tolerability of Lacosamide in Patients With Gain-of-function Nav1.7 Mutations Related Small Fiber Neuropathy PHASE3COMPLETED
Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and in COVID-19 Asymptomatic Patients PHASE2/PHASE3COMPLETED
Open Trail of γIFN for Friedreich Ataxia PHASE2COMPLETED
A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma PHASE2ACTIVE_NOT_RECRUITING
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure PHASE2COMPLETED
A Study to Assess the Safety and Efficacy of 3 Doses of ALX1-11 (50, 75, and 100µg) in the Treatment of Postmenopausal Osteoporosis PHASE2COMPLETED
Study of the Effects of Iron on Lung Blood Pressure at High Altitude PHASE2WITHDRAWN
Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease EARLY_PHASE1COMPLETED
Personalized Medicine Program on Myelodysplastic Syndromes: Characterization of the Patient's Genome for Clinical Decision Making and Systematic Collection of Real World Data to Improve Quality of Health Care nanCOMPLETED
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Natural History Study of FDXR Mutation-related Mitochondriopathy nanCOMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Ferroptosis Study in SF3B1-mutant Myelodysplastic Syndromes (FerMDS) nanRECRUITING
Hydroxychloroquin (HCQ) in chILD of Genetic Defect nanCOMPLETED
Hemochromatosis and Iron Overload Screening Study (HEIRS) nanCOMPLETED
Inflammatory Anemia Associated Parameters in Septic Patients nanUNKNOWN
Genetic Causes and Clinical Features of Childhood Interstitial Lung Diseases in China nanCOMPLETED
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy nanCOMPLETED
GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis nanUNKNOWN
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features nanUNKNOWN
Study of the Effects of Iron Levels on the Lungs at High Altitude nanCOMPLETED
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis nanNOT_YET_RECRUITING
Genes Influencing Iron Overload State nanCOMPLETED
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression nanRECRUITING
Serum NGAL IN Patients With Multiple Myeloma nanUNKNOWN
Iron Overload in African Americans nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a SFXN1 binder may also engage these)

ProteinNameSimilarity
Q63965 1.000 Q63965 →
Q99JR1 1.000 Q99JR1 →
Q5RD16 1.000 Q5RD16 →
B2LU20 1.000 B2LU20 →
Q9VN13 1.000 Q9VN13 →
A5A761 1.000 A5A761 →
SFXN3 Sideroflexin-3 1.000 landscape →
Q9JHY2 1.000 Q9JHY2 →
Q5E9M8 1.000 Q5E9M8 →
A6QP55 1.000 A6QP55 →
Q12029 0.999 Q12029 →
Q5FC79 0.999 Q5FC79 →
Q925N2 0.998 Q925N2 →
Q91V61 0.996 Q91V61 →
Q96NB2 0.996 Q96NB2 →
Q5EA43 0.996 Q5EA43 →
O13793 0.995 O13793 →
Q9VVW3 0.995 Q9VVW3 →
Q3T0M2 0.994 Q3T0M2 →
Q09201 0.994 Q09201 →
Q54NQ9 0.993 Q54NQ9 →
A8E7G5 0.990 A8E7G5 →
Q6P4A7 0.990 Q6P4A7 →
Q925N1 0.984 Q925N1 →
P53311 0.979 P53311 →
Q95QD1 0.978 Q95QD1 →
P38857 0.977 P38857 →
P00425 0.977 P00425 →
Q9VW12 0.977 Q9VW12 →
B4KZ16 0.976 B4KZ16 →