SHPRH

E3 ubiquitin-protein ligase SHPRH · Q149N8 · SHPRH on Sugi Atlas →

0 patent compounds predicted against SHPRH, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SHPRH by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Bortezomib in Intrahepatic Cholangiocellular Carcinoma PHASE3UNKNOWN
Effects of Genistein Aglycone in Glucocorticoid Induced Osteoporosis PHASE2/PHASE3UNKNOWN
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma PHASE2WITHDRAWN
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
CISH Inactivated TILs in the Treatment of NSCLC PHASE1/PHASE2WITHDRAWN
Phase II Study of Vandetanib in Individuals With Kidney Cancer PHASE2COMPLETED
A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering PHASE1/PHASE2COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis PHASE2UNKNOWN
Phase I Study of SC-43 Oral Solution in Subjects With Refractory Solid Tumors PHASE1WITHDRAWN
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
A Dose Escalation and Expansion Trial With BYON4228 Alone and in Combination in Patients With Advanced or Metastatic Solid Tumors PHASE1ACTIVE_NOT_RECRUITING
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease EARLY_PHASE1RECRUITING
Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery EARLY_PHASE1COMPLETED
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease nanUNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
Genetic Variation in TRAF3IP2 (rs13190932) nanRECRUITING
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors nanNOT_YET_RECRUITING
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
Value of MicroRNA30a in Philadelphia Positive Leukemic Patients nanUNKNOWN
Establishment of a Prospective Clinical-biological Database nanRECRUITING
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
The Activation of Hippo Pathway in Nasal Polyps nanUNKNOWN
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas nanACTIVE_NOT_RECRUITING
Comparison of the Human Papillomavirus (HPV) Type 16 E7-Specific Immune Response Between a Normal Population and Patients With Cervical Lesions nanUNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases nanNOT_YET_RECRUITING
RORC Genetic Polymorphism of Rheumatoid Arthritis nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a SHPRH binder may also engage these)

ProteinNameSimilarity
Q7TPQ3 1.000 Q7TPQ3 →
F1ND48 0.983 F1ND48 →
Q5XIX3 0.982 Q5XIX3 →
Q5RED8 0.980 Q5RED8 →
Q69Z66 0.979 Q69Z66 →
Q5RCV3 0.979 Q5RCV3 →
Q9BXT6 0.979 Q9BXT6 →
A0JMR6 0.979 A0JMR6 →
Q8NE18 0.979 Q8NE18 →
Q9Y620 0.979 Q9Y620 →
F6RIX4 0.978 F6RIX4 →
Q9DG67 0.978 Q9DG67 →
Q3B7T1 0.978 Q3B7T1 →
Q8NFZ0 0.978 Q8NFZ0 →
Q8NG08 0.977 Q8NG08 →
Q5QJC2 0.977 Q5QJC2 →
Q8C0W1 0.977 Q8C0W1 →
Q8R5K2 0.977 Q8R5K2 →
Q5R6Z9 0.977 Q5R6Z9 →
Q8K4J0 0.977 Q8K4J0 →
Q502W6 0.977 Q502W6 →
Q99MV5 0.977 Q99MV5 →
Q96T68 0.977 Q96T68 →
Q9XT62 0.977 Q9XT62 →
Q6DD21 0.976 Q6DD21 →
O60934 0.976 O60934 →
Q2HJ90 0.976 Q2HJ90 →
O35099 0.976 O35099 →
ERCC5 DNA excision repair protein ERCC-5 0.976 landscape →
O75943 0.976 O75943 →