SHROOM3

Protein Shroom3 · Q8TF72 · SHROOM3 on Sugi Atlas →

0 patent compounds predicted against SHROOM3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SHROOM3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia PHASE3COMPLETED
A Study of SHR-2173 in Participants With Primary IgA Nephropathy PHASE2RECRUITING
A Phase II Study of SHR-4602 as Montherapy or in Combination With Other Anti-tumor Therapies in Advanced Solid Tumors PHASE2NOT_YET_RECRUITING
Famitinib Plus Anti-PD1 Therapy for Advanced Urinary System Tumor, Advanced Gynecological Tumors PHASE2UNKNOWN
A Phase II Study of SHR-2173 Injection in Patients With Myasthenia Gravis PHASE2NOT_YET_RECRUITING
A TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF SHR-A1904 IN SUBJECTS WITH ADVANCED SOLID TUMORS PHASE1/PHASE2RECRUITING
Antihypertensive Effect of Rostafuroxin Compared With Losartan in Hypertensive Patients Bearing Specified Gene Mutations PHASE2UNKNOWN
A Trial of SHR-1701 With or Without Chemotherapy in Patients With Stage III NSCLC PHASE2UNKNOWN
Phase I Study on the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Subcutaneous Injection of SHR-2173 in Healthy Subjects PHASE1COMPLETED
A Trial of SHR-1703 in Asthma PHASE1UNKNOWN
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
Angiotensinogen Gene and Hypertension nanUNKNOWN
Family Blood Pressure Program - GENOA nanCOMPLETED
Identifying Genes Involved in Abnormal Blood Pressure - Hypertension SCOR nanCOMPLETED
Family Blood Pressure Program - HyperGEN nanCOMPLETED
Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs nanWITHDRAWN
Genes of Hypertension in African Americans nanCOMPLETED
Identification of Novel Molecular Markers for Vasospasm nanCOMPLETED
Familial Intracranial Aneurysm Study II nanCOMPLETED
SAPPHIRe III in Taiwan-Progression Evaluation and Cardiovascular Outcomes of Hypertensive Families nanUNKNOWN
Sodium Transport: Genetics and Hypertension nanCOMPLETED
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients nanCOMPLETED
The Role of Genetic Factors in the Development of Arterial Hypertension in the Kazakh Population nanCOMPLETED
Rheo-Erythrocrine Dysfunction as a Biomarker for RIC Treatment in Acute Ischemic Stroke nanCOMPLETED
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Urinary Kallikrein and Hypertension: A Prospective Study nanCOMPLETED
Genetic Analysis of Familial Hypertrophic Cardiomyopathy nanCOMPLETED
Genetic Epidemiology of Asthma in Costa Rica nanCOMPLETED
Chronic Obstructive Pulmonary Disease Gene Localization nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SHROOM3 binder may also engage these)

ProteinNameSimilarity
Q9QXN0 0.998 Q9QXN0 →
Q5SYE7 0.994 Q5SYE7 →
Q922B9 0.992 Q922B9 →
Q27IV2 0.992 Q27IV2 →
O88881 0.991 O88881 →
Q5HYW2 0.991 Q5HYW2 →
A2AHC3 0.991 A2AHC3 →
Q6R6L0 0.990 Q6R6L0 →
Q1W617 0.990 Q1W617 →
A2ALU4 0.990 A2ALU4 →
Q76I79 0.990 Q76I79 →
O95886 0.990 O95886 →
Q9JL04 0.989 Q9JL04 →
Q8CAF4 0.989 Q8CAF4 →
Q9Y2H5 0.989 Q9Y2H5 →
A6H5Y1 0.989 A6H5Y1 →
Q5DTX6 0.989 Q5DTX6 →
Q9Y4B5 0.989 Q9Y4B5 →
Q80U35 0.989 Q80U35 →
P97838 0.989 P97838 →
A2A9F4 0.989 A2A9F4 →
Q80Z38 0.989 Q80Z38 →
Q6PFD5 0.989 Q6PFD5 →
Q3KP66 0.989 Q3KP66 →
Q9P1A6 0.989 Q9P1A6 →
P59808 0.989 P59808 →
Q7TS75 0.989 Q7TS75 →
Q5VZ18 0.988 Q5VZ18 →
Q571I4 0.988 Q571I4 →
Q8BI29 0.988 Q8BI29 →