SIN3A — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SIN3A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Study on the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family.	nan	UNKNOWN
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Immune Cell Response to Stimuli	nan	RECRUITING
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Role of the Nuclear Pore Component RANBP2 in Inflammatory Responses to Viral Infections	nan	COMPLETED
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases	nan	NOT_YET_RECRUITING
Mapping Disease Pathways for Biliary Atresia	nan	RECRUITING
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
High Altitude Medical Research Expedition Himlung 2013 - a Study of Human Adaption to Hypoxia	nan	COMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Defining an Obesity QTL on Chromosome 3q	nan	COMPLETED
Genetic Variants Associated With Adolescent Suicide Attempts	nan	COMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.	nan	UNKNOWN
Defining the Brain Phenotype of Children With Williams Syndrome	nan	RECRUITING
Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives	nan	UNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins.	nan	UNKNOWN
Gene Analysis of Parkinson's Disease	nan	COMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease	nan	RECRUITING
Study of the Genetic Factors Involved in Autism and Related Disorders	nan	RECRUITING
Identification of a New Gene Involved in Hereditary Lipodystrophy	nan	COMPLETED
Family Blood Pressure Program - HyperGEN	nan	COMPLETED
The Phenotyping and Genotyping of Taiwanese Patients With Obstructive Sleep Apnea	nan	UNKNOWN
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas	nan	ACTIVE_NOT_RECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SIN3A binder may also engage these)

Protein	Name	Similarity
Q60520	—	1.000	Q60520 →
Q62141	—	0.994	Q62141 →
SMARCC2	SWI/SNF complex subunit SMARCC2	0.992	landscape →
Q96G25	—	0.988	Q96G25 →
P70210	—	0.987	P70210 →
Q9D7W5	—	0.987	Q9D7W5 →
Q6PDG5	—	0.986	Q6PDG5 →
A5D794	—	0.986	A5D794 →
F4HPA7	—	0.986	F4HPA7 →
O54772	—	0.985	O54772 →
Q6P9Z1	—	0.985	Q6P9Z1 →
Q80TJ1	—	0.985	Q80TJ1 →
Q90701	—	0.984	Q90701 →
KAT2A	Histone acetyltransferase KAT2A	0.984	landscape →
O75182	—	0.984	O75182 →
TEAD4	Transcriptional enhancer factor TEF-3	0.984	landscape →
Q69ZZ6	—	0.984	Q69ZZ6 →
CNOT1	CCR4-NOT transcription complex subunit 1	0.984	landscape →
O94915	—	0.984	O94915 →
Q3UQU0	—	0.984	Q3UQU0 →
O43439	—	0.984	O43439 →
SMARCC1	SWI/SNF complex subunit SMARCC1	0.984	landscape →
Q9H3P2	—	0.983	Q9H3P2 →
Q62296	—	0.983	Q62296 →
P97496	—	0.983	P97496 →
Q9EP53	—	0.983	Q9EP53 →
Q5R8Q4	—	0.983	Q5R8Q4 →
Q6GLR7	—	0.983	Q6GLR7 →
Q8BMP6	—	0.983	Q8BMP6 →
Q02225	—	0.983	Q02225 →