SLC19A1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1603722	1.00	8/20
SCHEMBL1603726	1.00	8/20
SCHEMBL1604607	0.78	8/20
SCHEMBL1604603	0.72	8/20
SCHEMBL1604705	0.69	8/20
SCHEMBL1604735	0.49	8/20
SCHEMBL1604731	0.46	8/20
SCHEMBL1604573	0.97	7/20
SCHEMBL1604578	0.97	7/20
SCHEMBL1605452	0.77	7/20
SCHEMBL1605457	0.77	7/20
SCHEMBL1604709	0.75	7/20
SCHEMBL1604545	0.72	7/20
SCHEMBL1604549	0.72	7/20
SCHEMBL1604520	0.69	7/20
SCHEMBL1604524	0.69	7/20
SCHEMBL1604587	0.62	7/20
SCHEMBL1604592	0.62	7/20
SCHEMBL1603741	0.62	7/20
SCHEMBL1603743	0.62	7/20

Clinical trials — most relevant to SLC19A1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Reducing Anemia in Pregnancy in India: the RAPIDIRON Trial	PHASE4	COMPLETED
Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies	PHASE4	COMPLETED
How Precision Diets, Through Gut Bacteria, Affect Anemia in Nepalese Adolescent	PHASE3	NOT_YET_RECRUITING
Antenatal Micronutrient Supplementation and Infant Survival	PHASE3	COMPLETED
A Placebo-controlled Trial of Folinic Acid in Children With ASD	PHASE2	RECRUITING
Study Using FolateScan to Identify Subjects With Folate Receptor-Positive Metastatic Renal Cell Carcinoma	PHASE2	COMPLETED
10-Propargyl-10-Deazaaminopterin in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma	PHASE1/PHASE2	COMPLETED
A Study Comparing CO-1.01 With Gemcitabine as First Line Therapy in Patients With Metastatic Pancreatic Adenocarcinoma (LEAP)	PHASE2	COMPLETED
Copper Histidine Therapy for Menkes Diseases	PHASE1/PHASE2	COMPLETED
Pyrimethamine for Intermediate/High-risk Myelodysplastic Syndromes (MDS)	PHASE1	WITHDRAWN
A Clinical Trial of SIBP-A19 Injection in the Treatment of Advanced Malignant Solid Tumor Patients	PHASE1	RECRUITING
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters	EARLY_PHASE1	COMPLETED
Understanding Methotrexate Induced Gastrointestinal Intolerance in Juvenile Idiopathic Arthritis and Childhood Leukemia	nan	COMPLETED
Assessing Colonic Folate Absorption & Metabolism	nan	UNKNOWN
PK/PD Investigation of Calciumfolinat in Blood, Tumor and Adjacent Mucosa in Patient With Colon Cancer	nan	UNKNOWN
DHFR 19 bp Deletion Polymorphism and Folic Acid Utilization	nan	COMPLETED
Influence of Iron and Foliate Transporters on Bioavailability of These Micronutrients in the Organism	nan	COMPLETED
Renal and Hepatic Clearance Following High-Dose Methotrexate in Childhood ALL	nan	COMPLETED
Food and Alcohol Behavior Study: Meaningful Enhancement	nan	UNKNOWN
Folic Acid Supplementation in Women of Child Bearing Age	nan	COMPLETED
Clinical and Laboratory Study of Methylmalonic Acidemia	nan	RECRUITING
Where is the Initial Site of Biotransformation of Folates in Humans?	nan	COMPLETED
Folic Acid Supplementation in Children With Sickle Cell Disease	nan	COMPLETED
The Effect of Folic Acid Supplementation and Pregnancy on the Folate Forms in Red Blood Cells	nan	COMPLETED
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy	nan	COMPLETED
Treating Oxidative Stress and the Metabolic Pathology of Autism	nan	COMPLETED
Bioavailability of Folate From a Mixed Diet Using a Stable Isotope Method	nan	COMPLETED
Validation of Urinary Biomarkers of Folate Status	nan	COMPLETED
Development of an Optimal Micronutrient Reference Range for Adults	nan	COMPLETED
Guanidinoacetic Acid With Creatine Compared With Creatine Alone for Tissue Bioenergetics, Hyperhomocysteinemia and Exercise Performance	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SLC19A1 binder may also engage these)

Protein	Name	Similarity
P41438	—	0.987	P41438 →
Q62866	—	0.985	Q62866 →
Q9EQN9	—	0.980	Q9EQN9 →
P42557	—	0.977	P42557 →
SLC19A2	Thiamine transporter 1	0.976	landscape →
A2A6C4	—	0.976	A2A6C4 →
Q9HCE9	—	0.975	Q9HCE9 →
Q8K0H7	—	0.975	Q8K0H7 →
Q9BZV2	—	0.974	Q9BZV2 →
Q5GH56	—	0.973	Q5GH56 →
Q9HBU9	—	0.972	Q9HBU9 →
Q4R877	—	0.971	Q4R877 →
Q6PB70	—	0.971	Q6PB70 →
D2HSA6	—	0.970	D2HSA6 →
Q9BY10	—	0.970	Q9BY10 →
Q91WD0	—	0.970	Q91WD0 →
Q8IUH8	—	0.970	Q8IUH8 →
Q8N370	—	0.969	Q8N370 →
Q96JT2	—	0.969	Q96JT2 →
Q498W5	—	0.969	Q498W5 →
Q99PL8	—	0.969	Q99PL8 →
Q5GH72	—	0.968	Q5GH72 →
Q0VC03	—	0.968	Q0VC03 →
Q5BKX6	—	0.968	Q5BKX6 →
Q9C0H2	—	0.968	Q9C0H2 →
A0JPH4	—	0.967	A0JPH4 →
Q6P6V6	—	0.967	Q6P6V6 →
Q3U5Q7	—	0.967	Q3U5Q7 →
Q9N0B3	—	0.967	Q9N0B3 →
Q9NPR9	—	0.967	Q9NPR9 →