SLC26A3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL24045105	1.00	10/20
SCHEMBL26687589	1.00	10/20
SCHEMBL30154899	1.00	10/20
SCHEMBL24045265	0.81	10/20
SCHEMBL24045264	0.79	10/20
SCHEMBL743580	0.77	10/20
SCHEMBL24045333	0.73	10/20
SCHEMBL26687628	0.73	10/20
SCHEMBL24045268	0.79	9/20
SCHEMBL24045240	0.69	9/20
SCHEMBL24045106	1.00	8/20
SCHEMBL26687854	0.82	8/20
SCHEMBL24045273	0.84	7/20
SCHEMBL24045277	0.83	7/20
SCHEMBL26687910	0.82	7/20
SCHEMBL24045275	0.78	7/20
SCHEMBL24045255	0.71	7/20
SCHEMBL6559983	0.43	7/20
SCHEMBL24045270	0.74	6/20
SCHEMBL24045271	0.74	6/20

Clinical trials — most relevant to SLC26A3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Febuxostat, Blood Pressure and the Intrarenal Renin-Angiotensin System (RAS)	PHASE4	COMPLETED
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation	PHASE2/PHASE3	UNKNOWN
Secretin in Ex-situ Liver Perfusion	PHASE1/PHASE2	ENROLLING_BY_INVITATION
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops	PHASE2	UNKNOWN
Effect of, OAT3, on the Renal Secretion of Cefotaxime	PHASE1	COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters	EARLY_PHASE1	COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Oxalate and Citrate in Humans - Response to Citrate	nan	RECRUITING
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts	nan	COMPLETED
Clinical Phenotypic Characteristics of SC26A4	nan	UNKNOWN
SLC13A5 Deficiency Natural History Study - Remote Only	nan	ENROLLING_BY_INVITATION
Comparison Between Ultra-low-dose Computed Tomography and Lung MRI in Cystic Fibrosis	nan	COMPLETED
Gene Expression in Inflammatory Bowel Disease	nan	ENROLLING_BY_INVITATION
Genotype-phenotype Correlation of SLC26A4 in CI Patients With EVA	nan	UNKNOWN
Bronchial Trans-epithelial Transport in Patients With Idiopathic Multiple Dilations of the Bronchi	nan	COMPLETED
Oxalate and Citrate	nan	RECRUITING
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital	nan	UNKNOWN
The Effects of Isotonic and Hypertonic Saline Infusion on Renal Biomarkers in Healthy Young Subjects	nan	COMPLETED
Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter	nan	COMPLETED
Impact of Polymorphisms of OAT1, OAT3, and OCT2 on Transportation of Potential Nephrotoxic Drugs	nan	COMPLETED
Bile Acid Effects in Fetal Arrhythmia Study	nan	UNKNOWN
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes	nan	RECRUITING
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders	nan	UNKNOWN
Comparative Effects of Mechanical and Manual Airway Clearance Techniques in Cystic Fibrosis	nan	NOT_YET_RECRUITING
POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS	nan	NOT_YET_RECRUITING
Muscle Endurance in Children With Cystic Fibrosis	nan	COMPLETED
ADPKD Alterations in Hepatic Transporter Function	nan	COMPLETED
Sweat Response, Sweat Composition and Thermoregulatory Response to Exercise in Heat in Adults With Cystic Fibrosis on Modulator Therapy.	nan	UNKNOWN
A Prospective Study of Advanced Diagnostics in People With an Unclear Diagnosis of Cystic Fibrosis	nan	NOT_YET_RECRUITING
Effects of Mycophenolate Mofetil in Cystic Fibrosis Lung Transplant Patients	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a SLC26A3 binder may also engage these)

Protein	Name	Similarity
Q924C9	—	0.998	Q924C9 →
Q9WVC8	—	0.997	Q9WVC8 →
Q69DJ1	—	0.990	Q69DJ1 →
P50443	—	0.986	P50443 →
Q9BEG8	—	0.985	Q9BEG8 →
Q7T2C4	—	0.985	Q7T2C4 →
Q9EPH0	—	0.983	Q9EPH0 →
Q65AC2	—	0.983	Q65AC2 →
P58743	—	0.982	P58743 →
Q62273	—	0.981	Q62273 →
Q9GJY3	—	0.980	Q9GJY3 →
Q99NH7	—	0.980	Q99NH7 →
O70531	—	0.979	O70531 →
Q9LW86	—	0.979	Q9LW86 →
Q9MAX3	—	0.978	Q9MAX3 →
Q9JKQ2	—	0.978	Q9JKQ2 →
D7PC76	—	0.978	D7PC76 →
Q8GYH8	—	0.977	Q8GYH8 →
O04289	—	0.977	O04289 →
O04722	—	0.976	O04722 →
A0FKN5	—	0.976	A0FKN5 →
P53391	—	0.975	P53391 →
Q8BU91	—	0.974	Q8BU91 →
P53393	—	0.973	P53393 →
Q94LW6	—	0.973	Q94LW6 →
Q8CIW6	—	0.972	Q8CIW6 →
P53392	—	0.971	P53392 →
Q9FEP7	—	0.971	Q9FEP7 →
Q9SAY1	—	0.968	Q9SAY1 →
Q7LBE3	—	0.968	Q7LBE3 →