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Sugi Predict / Targets / SPAG5

SPAG5

Sperm-associated antigen 5 · Q96R06 · SPAG5 on Sugi Atlas →

0 patent compounds predicted against SPAG5, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SPAG5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men PHASE3ACTIVE_NOT_RECRUITING
PCSK9 Inhibitor Treatment for Patients With SPG5 PHASE1/PHASE2UNKNOWN
Intra-Testicular Transplantation of Autologous Stem Cells for Treatment of Non-Obstructive Azoospermia Male Infertility. PHASE1/PHASE2UNKNOWN
Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer PHASE1/PHASE2WITHDRAWN
BCG Modulation of the recMAGE-A3 + AS15 ASCI Response in the Treatment of Non Muscle Invasive Bladder Cancer (NMIBC) Patients PHASE1COMPLETED
The Role of HE4 in the Follow-up of Advanced Ovarian, Fallopian Tube and Primary Peritoneal Cancer nanUNKNOWN
Serum Prostatic Specific Antigen Changes After Bipolar and Monopolar TURP nanUNKNOWN
Study of Sperm Molecular Factors Implicated in Male Fertility nanCOMPLETED
Consequences of Mutations in the SPG7 Gene at the Heterozygous State nanCOMPLETED
Imaging Biomarkers in Spastic Paraplegia Type 5 nanCOMPLETED
Phenotypes, Biomarkers and Pathophysiology in Spastic Ataxias nanUNKNOWN
Genetic Causes of Male Infertility nanCOMPLETED
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study nanCOMPLETED
Reproductive Outcomes After Intracytoplasmic Sperm Injection (ICSI) With Surgically Retrieved Sperm. nanACTIVE_NOT_RECRUITING
Serum Retinoic Acid Induced Protein 14 (RAI14) and Metastasis Associated Cancer Colon -1 (MACC-1) in Breast Cancer nanUNKNOWN
Investigation Into Detection of Prostate Cancer Using Voided Urine (Prostate VPAC) nanRECRUITING
Azoospermia Patients nanRECRUITING
Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI) nanRECRUITING
Study of Gene Associations and Infertility nanENROLLING_BY_INVITATION
Genetic Studies Spermatogenic Failure nanCOMPLETED
Efficacy Study of a Food Supplement With Myo-inositol, N-Acetyl-Cystein, Zinc and Vitamins on Sperm DNA Fragmentation nanRECRUITING
Outcome of Using Sperm Bound to the Zona Pellucida of Immature Oocytes for Intracytoplasmic Sperm Injection (ICSI) nanCOMPLETED
Genetics of Atherosclerosis in Mexican Americans nanCOMPLETED
Risk of Recurrence of de Novo Mutations: Research and Quantification of Paternal Germinal Mosaicism by the Combined Use of Genomic Tools nanCOMPLETED
Warfarin Effects on Male Fertility After Cardiac Surgery nanNOT_YET_RECRUITING
Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer nanCOMPLETED
Human Epididymis Protein 4 in Endometrial Carcinoma nanCOMPLETED
Epididymal U.S Findings in Asthenozoospermic &Correlation With L.Carnitine Level nanUNKNOWN
Familial Prostate Cancer nanCOMPLETED
Screening of Low Responders for Aneuploidy to Improve Reproductive Efficiency nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SPAG5 binder may also engage these)

ProteinNameSimilarity
Q7TME2 — 0.997 Q7TME2 →
Q96SN8 — 0.993 Q96SN8 →
I6L899 — 0.992 I6L899 →
P0CG33 — 0.992 P0CG33 →
Q66HB6 — 0.992 Q66HB6 →
P0DO97 — 0.991 P0DO97 →
Q19UN5 — 0.991 Q19UN5 →
Q9UJT2 — 0.991 Q9UJT2 →
F8WBI6 — 0.990 F8WBI6 →
Q3V0F0 — 0.990 Q3V0F0 →
Q8K389 — 0.990 Q8K389 →
Q9Y6A5 — 0.990 Q9Y6A5 →
P57680 — 0.990 P57680 →
Q0KK56 — 0.990 Q0KK56 →
Q9Z221 — 0.990 Q9Z221 →
A6H5Y1 — 0.990 A6H5Y1 →
Q6PCQ0 — 0.989 Q6PCQ0 →
Q0D2H9 — 0.989 Q0D2H9 →
A6NC78 — 0.989 A6NC78 →
Q9WVQ0 — 0.989 Q9WVQ0 →
H3BPF8 — 0.989 H3BPF8 →
Q5RHB5 — 0.989 Q5RHB5 →
Q811D2 — 0.989 Q811D2 →
A6NDN3 — 0.989 A6NDN3 →
A6NDK9 — 0.989 A6NDK9 →
Q9Y448 — 0.989 Q9Y448 →
Q9JLH5 — 0.988 Q9JLH5 →
RNF213 E3 ubiquitin-protein ligase RNF213 0.988 landscape →
Q8BLR5 — 0.988 Q8BLR5 →
Q9D9Z1 — 0.988 Q9D9Z1 →