SPOUT1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SPOUT1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Genomic and Transcriptomic Predictors of Sequential SG Sensitivity After T-DXd in ER+/HER2-Low Metastatic Breast Cancer	PHASE2	RECRUITING
Antibiotics, Gastric Bypass, and the Microbiome	PHASE1	COMPLETED
Microbiome and Metagenome in Percutaneous Osseointegrated Prostheses (MMPOP)	nan	COMPLETED
Trichomonas Vaginalis Genotyping in Upper Egypt	nan	UNKNOWN
Effect of Beta-Glucan on Cholesterol Lowering	nan	COMPLETED
Novel Diagnostic Methods to Identify External Ventricular Drain Associated Infections	nan	UNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis	nan	COMPLETED
Study of Faecal Bacteria Detection in Early Screening and Diagnosis of GC	nan	UNKNOWN
Clinical Impact of 16S rDNA PCR	nan	UNKNOWN
Ocular Surface Microbiome in Dry Eye Patients	nan	COMPLETED
The Gut Microbiome in Diverticulitis and Diverticulosis	nan	WITHDRAWN
Treatment of Initial Clostridium Difficile Infection	nan	COMPLETED
Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes	nan	ACTIVE_NOT_RECRUITING
Microbiome Establishment in Preterm Infants	nan	UNKNOWN
NUTRIPROTECT-Children Nutrition as a Protective or Health-risk Factor	nan	COMPLETED
Study of Sperm Molecular Factors Implicated in Male Fertility	nan	COMPLETED
The Salivary and Faecal Microbiome of Recurrent Aphthous Stomatitis Patients Before and After Treatment With Probiotics	nan	COMPLETED
Indwelling Device-associated Biofilms	nan	UNKNOWN
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC	nan	UNKNOWN
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Alpha Defensin and 16S rRNA Gene in Diagnosis of PJI	nan	UNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Impact of Direct-acting Antiviral Drugs on The Patterns of Gut Microbiota in Patients With HCV Related Chronic Liver Diseases	nan	COMPLETED
Clostridium Difficile Infection (CDI) in Hematologic Patients.	nan	UNKNOWN
Safety and Efficacy of Lactococcus Lactis Probiotic Bacteria for the Treatment of Chronic Rhinosinusitis	nan	COMPLETED
Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic Encephalopathy	nan	UNKNOWN
The Influence of the Microbiome on the Pharmacokinetics of Flavan-3-ols	nan	COMPLETED
Determining Bacterial Communities in the Lungs of HIV-infected Individuals With COPD in Uganda.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SPOUT1 binder may also engage these)

Protein	Name	Similarity
Q3UHX9	—	1.000	Q3UHX9 →
Q66ID3	—	0.991	Q66ID3 →
EMG1	Ribosomal RNA small subunit methyltransferase	0.986	landscape →
Q06287	—	0.986	Q06287 →
A1Z830	—	0.983	A1Z830 →
Q9XX15	—	0.983	Q9XX15 →
Q8WYJ6	—	0.982	Q8WYJ6 →
P06623	—	0.982	P06623 →
Q7YR39	—	0.981	Q7YR39 →
Q5XI69	—	0.981	Q5XI69 →
Q767K6	—	0.981	Q767K6 →
Q9W3C1	—	0.981	Q9W3C1 →
Q9W4J5	—	0.981	Q9W4J5 →
Q6P4W5	—	0.980	Q6P4W5 →
Q41140	—	0.980	Q41140 →
O60231	—	0.980	O60231 →
P16098	—	0.980	P16098 →
Q5BJS0	—	0.980	Q5BJS0 →
P09445	—	0.980	P09445 →
Q5RJS9	—	0.980	Q5RJS9 →
Q9P8P7	—	0.980	Q9P8P7 →
P0A699	—	0.980	P0A699 →
Q9UQ90	—	0.980	Q9UQ90 →
Q24087	—	0.979	Q24087 →
Q7TND5	—	0.979	Q7TND5 →
Q8IUF1	—	0.979	Q8IUF1 →
P93834	—	0.979	P93834 →
Q5ZMN2	—	0.979	Q5ZMN2 →
Q10950	—	0.979	Q10950 →
F4IDQ6	—	0.979	F4IDQ6 →