SRMS — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1363195	1.00	3/20
SCHEMBL1362165	0.90	3/20
SCHEMBL1361786	0.89	3/20
SCHEMBL1362874	0.87	3/20
SCHEMBL1361734	0.83	3/20
SCHEMBL1363069	0.83	3/20
SCHEMBL1363318	0.83	3/20
SCHEMBL1361749	0.83	3/20
SCHEMBL1361783	0.81	3/20
SCHEMBL1362380	0.79	3/20
SCHEMBL1363726	0.79	3/20
SCHEMBL1363892	0.76	3/20
SCHEMBL1363399	0.75	3/20
SCHEMBL1361498	0.74	3/20
SCHEMBL1363154	0.73	3/20
SCHEMBL1362918	0.72	3/20
SCHEMBL1362563	0.71	3/20
SCHEMBL1363910	0.69	3/20
SCHEMBL1361634	0.68	3/20
SCHEMBL1362547	0.68	3/20

Clinical trials — most relevant to SRMS by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Postpartum Primaquine in Breast Milk	PHASE4	COMPLETED
Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases	PHASE2	NOT_YET_RECRUITING
Proteomic Profiling for Congenital Diaphragmatic Hernia	nan	UNKNOWN
Serum and Cellular Biomarkers for Aortic Valve Stenosis	nan	UNKNOWN
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Proteomic Profiling to Reveal Novel Prognostic Markers for Neurological Outcome Following Resuscitation	nan	COMPLETED
Correlation Study of Atrophic Gastritis and Dyspepsia Symptoms	nan	RECRUITING
Analysis of Salivary Proteins in Young Children as an Device to Improve Caries Risk Assessment	nan	RECRUITING
Identification of Biomarkers Associated With Human Hepatocellular Carcinoma by SELDI	nan	UNKNOWN
Direct Molecular Characterization of Bacteria From ICU and From the REHAB	nan	COMPLETED
Effects of Gallotannins on the Gut Microbiome and How it Affects Inflammatory Markers Among Obese Individuals.	nan	ACTIVE_NOT_RECRUITING
Choroid Plexus Dysfunction in Neurological Diseases	nan	RECRUITING
Recompensation in Alcohol Related Hepatitis	nan	RECRUITING
Salivary Proteome in Response to Non-surgical Periodontal Treatment	nan	COMPLETED
Effects of Interval Training Effects on Cardiac Fibrosis	nan	COMPLETED
Pathogenesis and Management of M. Ulcerans Disease, Buruli Ulcer	nan	UNKNOWN
Direct Diagnosis of Disseminated Lyme Borreliosis.	nan	UNKNOWN
Long Term Prediction of MASH-related HCC Risk by Proteomics	nan	NOT_YET_RECRUITING
Predictive Role of New Biomarkers for Hypersensitive Patients to Radiation in Breast Cancer (BIORISE)	nan	ACTIVE_NOT_RECRUITING
Effect of Mepolizumab on Severe Eosinophilic Asthma	nan	UNKNOWN
Discovery of New Circulating Biomarkers of Coronary Atherosclerosis	nan	COMPLETED
Breast Cancer and Its Relationship With the Microbiota	nan	ACTIVE_NOT_RECRUITING
Phosphoproteomic Profile of Children With Down Syndrome	nan	COMPLETED
Arterial Composition and Cardiovascular Outcome in DIabeteS	nan	UNKNOWN
Optimized Remission in Alcohol-related Liver Cirrhosis	nan	RECRUITING
Proteomic Pattern in Female Stress Urinary Incontinence: a Pilot Study	nan	COMPLETED
Identification of Plasma Biomarkers for Early Diagnosis of Transplant-associated Thrombotic Microangiopathy	nan	RECRUITING
Identification of Biomarkers for Early Detection of Pancreatic Cancer	nan	COMPLETED
Ticopa Serum Analysis: an Analysis of Blood Samples From the TICOPA Study	nan	UNKNOWN
MOLECULAR REGULATION OF MUSCLE GLUCOSE METABOLISM (AIMS 2A, 2B, 3)	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SRMS binder may also engage these)

Protein	Name	Similarity
Q62270	—	0.996	Q62270 →
MATK	Megakaryocyte-associated tyrosine-protein kinase	0.993	landscape →
PTK6	Protein-tyrosine kinase 6	0.993	landscape →
P41243	—	0.993	P41243 →
P41242	—	0.987	P41242 →
P42682	—	0.983	P42682 →
Q64434	—	0.982	Q64434 →
Q99ML2	—	0.981	Q99ML2 →
TNK1	Non-receptor tyrosine-protein kinase TNK1	0.981	landscape →
JAK3	Tyrosine-protein kinase JAK3	0.978	landscape →
P23049	—	0.977	P23049 →
Q63474	—	0.977	Q63474 →
Q8BYG9	—	0.976	Q8BYG9 →
P0C0K6	—	0.976	P0C0K6 →
FRK	Tyrosine-protein kinase FRK	0.976	landscape →
O09127	—	0.976	O09127 →
Q922K9	—	0.975	Q922K9 →
EPHB4	Ephrin type-B receptor 4	0.975	landscape →
Q03146	—	0.975	Q03146 →
P29321	—	0.975	P29321 →
Q0VBZ0	—	0.974	Q0VBZ0 →
TXK	Tyrosine-protein kinase TXK	0.974	landscape →
P43404	—	0.974	P43404 →
P25020	—	0.974	P25020 →
P0C0K7	—	0.974	P0C0K7 →
DDR1	Epithelial discoidin domain-containing receptor 1	0.974	landscape →
P51840	—	0.974	P51840 →
P63185	—	0.973	P63185 →
P51839	—	0.973	P51839 →
P00526	—	0.973	P00526 →