SYNGR2

Synaptogyrin-2 · O43760 · SYNGR2 on Sugi Atlas →

0 patent compounds predicted against SYNGR2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to SYNGR2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Ketamine Treatment Effects on Synaptic Plasticity in Depression PHASE4COMPLETED
Prehospital Early Administration of Ketamine for Status Epilepticus in Epileptic Kids (PEAK-SEEK) PHASE2/PHASE3RECRUITING
The Synapse Project PHASE2COMPLETED
Pharmacological Treatment of Rett Syndrome With Glatiramer Acetate (Copaxone) PHASE2COMPLETED
Study to Assess Safety and Efficacy of Fingolimod in Children With Rett Syndrome PHASE1/PHASE2COMPLETED
Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder PHASE2COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
MEG Study of Acute STX209 Effects in ASD EARLY_PHASE1COMPLETED
Phenylbutyrate for Monogenetic Developmental and Epileptic Encephalopathy EARLY_PHASE1ACTIVE_NOT_RECRUITING
Multicenter Study of Patients With SHANK3 Mutations: Identification of Genes Modificators in Phelan-McDermid Syndrome (EUQ13) nanNOT_YET_RECRUITING
STXBP1 and SYNGAP1 Related Disorders Natural History Study nanRECRUITING
Comparing Outcomes of Theta Burst Stimulation in Depression Using Advanced PET Imaging nanNOT_YET_RECRUITING
Study of the Genetic Factors Involved in Autism and Related Disorders nanRECRUITING
NTRK 1,2,3 Rearrangements in Patients With Solid Tumors nanACTIVE_NOT_RECRUITING
Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services nanUNKNOWN
Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome. nanUNKNOWN
Neurophysiologic Biomarkers in Rett Syndrome nanRECRUITING
Neuropsychopathological Study of Autism nanUNKNOWN
Susceptibility Genes in Autism Spectrum Disorders nanCOMPLETED
Mitochondrial Dysfunction in Phelan-McDermid Syndrome nanCOMPLETED
miR-142-3p as Potential Biomarker of Synaptopathy in MS nanUNKNOWN
CAMK2-related Synapthopathies Natural History Study nanRECRUITING
Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients nanNOT_YET_RECRUITING
From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1 nanCOMPLETED
Cenobamate Efficacy in Individuals With Autoimmune Epilepsy nanENROLLING_BY_INVITATION
Phenotypic Exploration of Autism Spectrum Disorders Retrospective and Prospective Data nanRECRUITING
Standard Amblyopia Therapy in Adult Amblyopes nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SYNGR2 binder may also engage these)

ProteinNameSimilarity
A8MWL6 1.000 A8MWL6 →
Q5R703 1.000 Q5R703 →
A7E3W5 0.999 A7E3W5 →
O43759 0.999 O43759 →
O54980 0.999 O54980 →
O55100 0.997 O55100 →
O55101 0.996 O55101 →
Q62876 0.996 Q62876 →
Q8R191 0.994 Q8R191 →
Q7JYV2 0.993 Q7JYV2 →
O76735 0.991 O76735 →
P08247 0.987 P08247 →
A2VE58 0.987 A2VE58 →
O43761 0.986 O43761 →
P20488 0.986 P20488 →
P22831 0.986 P22831 →
Q62277 0.985 Q62277 →
Q8BGN8 0.984 Q8BGN8 →
A6H7B0 0.982 A6H7B0 →
P07825 0.981 P07825 →
Q75IC7 0.981 Q75IC7 →
Q9C5W7 0.981 Q9C5W7 →
Q5YJC1 0.981 Q5YJC1 →
Q2YDD6 0.981 Q2YDD6 →
Q8TBG9 0.981 Q8TBG9 →
Q9Y342 0.978 Q9Y342 →
P47987 0.978 P47987 →
A3KQ86 0.978 A3KQ86 →
Q95T12 0.978 Q95T12 →
Q9JJK1 0.977 Q9JJK1 →