SYVN1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to SYVN1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From Real World	PHASE4	UNKNOWN
Serum Calprotectin Level in Patients With Rheumatoid Arthritis and Osteoarthritis	PHASE4	UNKNOWN
Molecular Biomarkers Associated With Degenerative Joint Disease in the Knee	nan	COMPLETED
MSUS Versus Serum Survivin and Lubricin Levels in Evaluation of Disease Activity in JIA	nan	UNKNOWN
Identification of Novel Molecular Targets for Rheumatoid Arthritis Patients	nan	UNKNOWN
Screening of Specific Genes for Pigmented Villous Nodular Synovitis	nan	COMPLETED
Genetics of Rheumatoid Arthritis	nan	COMPLETED
Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease, and Related Conditions	nan	RECRUITING
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Phenotype/Genotype Correlation in a Family With Early Onset Osteoarthritis	nan	COMPLETED
Identification of Genomic Biomarkers for Rheumatoid Arthritis With Late Onset	nan	WITHDRAWN
The Relation Between Macrophage Migration Inhibitory Factor (MIF) and 25(OH) Vitamin D3 Serum Levels in Rheumatoid Arthritis	nan	UNKNOWN
Genetic Determinants of Ankylosing Spondylitis Severity	nan	COMPLETED
Synovial Tissue as a Biomarker in the Early Management of Osteoarthritis	nan	RECRUITING
CTHRC1: A Biomarker for Evaluation of Rheumatoid Arthritis Disease Activity	nan	UNKNOWN
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin	nan	UNKNOWN
Identification of Molecular Marker of Coagulase-negative Staphylococci for the Diagnosis of Prosthetic Joint Infections	nan	UNKNOWN
Translating Articular Biomarkers Into Diagnoses	nan	RECRUITING
Genetic Registry for Rheumatoid Arthritis	nan	COMPLETED
Genetics and Mechanisms of Rheumatoid Arthritis	nan	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Exercise on microRNA in Rheumatoid Arthritis	nan	COMPLETED
Clinical Study of Desuzumab in the Treatment of Knee Osteoarthritis	nan	RECRUITING
Genetic Analysis of Psoriasis and Psoriatic Arthritis	nan	COMPLETED
18F-FDG PET/TC in TIR3A e TIR3B	nan	ENROLLING_BY_INVITATION
The Genetic and the Functional Study of DNA Repair System and the Susceptibility to Rheumatoid Arthritis	nan	COMPLETED
Pharmacogenomics of Anti-TNF (Anti-tumor Necrosis Factor) Treatment in Patients With Rheumatoid Arthritis	nan	UNKNOWN
GARM II: A Study on the Genetics of Age-related Maculopathy	nan	ACTIVE_NOT_RECRUITING
Mechanism of Action of Ustekinumab in Psoriatic Arthritis	nan	UNKNOWN
Early Biomarkers for ARthritic PAIN to Guide Improved Treatments for Arthritis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a SYVN1 binder may also engage these)

Protein	Name	Similarity
Q9DBY1	—	1.000	Q9DBY1 →
Q6NRL6	—	0.991	Q6NRL6 →
Q803I8	—	0.989	Q803I8 →
Q5XHH7	—	0.987	Q5XHH7 →
Q90YH8	—	0.966	Q90YH8 →
Q6P4P2	—	0.965	Q6P4P2 →
Q5PQS6	—	0.964	Q5PQS6 →
Q8IWV8	—	0.964	Q8IWV8 →
Q6R755	—	0.962	Q6R755 →
Q5R7S4	—	0.962	Q5R7S4 →
Q8WXG6	—	0.962	Q8WXG6 →
Q9JJV8	—	0.961	Q9JJV8 →
P22682	—	0.961	P22682 →
Q9UPW6	—	0.961	Q9UPW6 →
Q9H0W8	—	0.961	Q9H0W8 →
Q3UHE1	—	0.960	Q3UHE1 →
A9JRA0	—	0.960	A9JRA0 →
BCL2	Apoptosis regulator Bcl-2	0.960	landscape →
Q6P8G8	—	0.960	Q6P8G8 →
Q01826	—	0.960	Q01826 →
Q80U28	—	0.960	Q80U28 →
P10417	—	0.960	P10417 →
Q5RH73	—	0.960	Q5RH73 →
Q5R9W1	—	0.960	Q5R9W1 →
Q9H3S7	—	0.960	Q9H3S7 →
Q60611	—	0.960	Q60611 →
O60337	—	0.960	O60337 →
Q96D05	—	0.960	Q96D05 →
Q4KUS2	—	0.960	Q4KUS2 →
Q8C561	—	0.959	Q8C561 →