TBRG4

FAST kinase domain-containing protein 4 · Q969Z0 · TBRG4 on Sugi Atlas →

0 patent compounds predicted against TBRG4, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to TBRG4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Weight Loss Study: Genetics and Response to Naltrexone/Bupropion PHASE4RECRUITING
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus PHASE3UNKNOWN
The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients PHASE1/PHASE2WITHDRAWN
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes PHASE2RECRUITING
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors PHASE1COMPLETED
Acute Effect of HP-211 (Axulin) on Blood Glucose and Serum Insulin Responses in Healthy Lean and Overweight Humans PHASE1COMPLETED
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
Breakpoint Analysis of de Novo Apparently Balanced Chromosomal Translocations EARLY_PHASE1COMPLETED
The Role of TBC1D4 in Exercise- and Insulin-induced Glucose Metabolism in Human Skeletal Muscle nanCOMPLETED
Molecular Pathways Related to Short-term Fasting Response nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
New Genes Involved in Molecular Etiology of Rett Syndrome Through DNA Microarray Comparative Genomic Hybridization nanCOMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA) nanCOMPLETED
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Human Epilepsy Genetics--Neuronal Migration Disorders Study nanRECRUITING
Natural History of Acquired and Inherited Bone Marrow Failure Syndromes nanRECRUITING
Molecular Mechanisms of Exercise Benefits to Insulin Resistant People nanCOMPLETED
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Genetics of Recurrent Early Onset Major Depression nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte nanCOMPLETED
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Biomarker Research in Inherited Movement Disorders nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TBRG4 binder may also engage these)

ProteinNameSimilarity
Q91YM4 1.000 Q91YM4 →
Q3SZK4 1.000 Q3SZK4 →
Q5M9G9 1.000 Q5M9G9 →
Q7YS91 1.000 Q7YS91 →
Q6PA48 0.995 Q6PA48 →
Q6DJ55 0.990 Q6DJ55 →
FASTKD5 FAST kinase domain-containing protein 5, mitochondrial 0.990 landscape →
Q95KD0 0.989 Q95KD0 →
Q14CZ7 0.987 Q14CZ7 →
Q5RFI6 0.985 Q5RFI6 →
Q68FN9 0.985 Q68FN9 →
Q8BSN9 0.985 Q8BSN9 →
Q7TMV3 0.983 Q7TMV3 →
Q58CX2 0.982 Q58CX2 →
Q6DI86 0.982 Q6DI86 →
Q9JIX9 0.980 Q9JIX9 →
Q0V9L1 0.979 Q0V9L1 →
Q6GQ66 0.979 Q6GQ66 →
Q6PB66 0.978 Q6PB66 →
Q99MQ3 0.978 Q99MQ3 →
Q2KI62 0.978 Q2KI62 →
Q9EPK6 0.977 Q9EPK6 →
Q8BM55 0.977 Q8BM55 →
Q14C51 0.977 Q14C51 →
Q0IHP3 0.977 Q0IHP3 →
A1L1L2 0.976 A1L1L2 →
Q28DE0 0.976 Q28DE0 →
Q8C3S2 0.976 Q8C3S2 →
E1BP36 0.976 E1BP36 →
E0CZ22 0.976 E0CZ22 →