TFRC — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to TFRC by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Bovine Lactoferrin to Prevent and Cure Iron Deficiency and Iron Deficiency Anemia in Complicated Pregnancies	PHASE4	COMPLETED
Intravenous Iron for Treatment of Anaemia Before Cardiac Surgery	PHASE4	COMPLETED
Clinical Burden of Anemia in Inflammatory Bowel Disease: Therapeutic Trial	PHASE3	UNKNOWN
Analysis of the Modulation of Serum Hepcidin Level in Response to Iron Oral Intake: Potential Interest for the Differential Diagnosis Between Ferroportin Disease and Dysmetabolic Hepatosiderosis.	PHASE2	COMPLETED
A Single-arm Trial of Roxadustat Combined With Retinoic Acid in the Treatment of Refractory Low-risk MDS	PHASE1/PHASE2	NOT_YET_RECRUITING
Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis	nan	UNKNOWN
Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis	nan	NOT_YET_RECRUITING
Diagnostic of Iron Deficiency by Means of Non Invasive Measurement of Zink Protoporphyrin IX	nan	COMPLETED
Inflammatory Anemia Associated Parameters in Septic Patients	nan	UNKNOWN
Effects of Lactoferrin-enriched Whey on Iron Status in Females	nan	UNKNOWN
Daily vs Intermittent Iron Therapy in Pregnancy	nan	COMPLETED
Effect of Taking a Single Tablet of Iron on Insulin Secretion	nan	COMPLETED
Is Helicobacter Pylori Infection a Cause or Treatment Failure of Iron Deficiency Anemia in Children in Bangladesh?	nan	COMPLETED
Iron Metabolism Parameters At First Trimester and preGnancy outcomE	nan	UNKNOWN
Protocol for the Assessment of Variability in Histology and Gene Expression in Bariatric Surgery Patients.	nan	COMPLETED
The Effect of Ovotransferrin and Lactoferrin on Iron Absorption From Ferrous Sulfate in Adult Women	nan	COMPLETED
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features	nan	UNKNOWN
Effectiveness of a Biosimilar Epoetin Alfa in Stable 'End Stage Renal Failure'	nan	UNKNOWN
Genes-in-Action - Hepcidin Regulation of Iron Supplementation	nan	COMPLETED
The Relation Between Adiposity, Inflammation, Glycaemia and Iron Absorption	nan	COMPLETED
Out Come Study To Define Laboratory Parameters That Are Best Suited to Diagnose Functional Iron Deficiency	nan	COMPLETED
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants	nan	COMPLETED
Candidate Gene for Hyperferritinemia	nan	UNKNOWN
Transferrin Saturation and Asthenia in Hemochromatosis	nan	COMPLETED
Hemochromatosis and Iron Overload Screening Study (HEIRS)	nan	COMPLETED
Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)	nan	COMPLETED
Iron Status in Infants in Ethiopia.	nan	UNKNOWN
Cohort of Patients With Rare Iron Overloads Excluding C282Y Homozygosity	nan	COMPLETED
Brain Manganese Deposition in High Risk Neonates	nan	COMPLETED
Different Oral Iron Dosing Regimens in Treatment of Iron Deficency Anemia in Patients With Chronic Kidney Disease	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a TFRC binder may also engage these)

Protein	Name	Similarity
Q5RDH6	—	1.000	Q5RDH6 →
Q2V905	—	1.000	Q2V905 →
Q9GLD3	—	1.000	Q9GLD3 →
Q07891	—	1.000	Q07891 →
Q8HZV3	—	1.000	Q8HZV3 →
Q62351	—	1.000	Q62351 →
Q9MYZ3	—	1.000	Q9MYZ3 →
Q99376	—	0.998	Q99376 →
Q90997	—	0.996	Q90997 →
Q7M758	—	0.984	Q7M758 →
P57716	—	0.984	P57716 →
Q9CQF9	—	0.984	Q9CQF9 →
Q9WTZ2	—	0.984	Q9WTZ2 →
Q9Z2A8	—	0.983	Q9Z2A8 →
Q9WTZ3	—	0.982	Q9WTZ3 →
O54697	—	0.981	O54697 →
NCSTN	Nicastrin	0.981	landscape →
Q8CGU6	—	0.981	Q8CGU6 →
MBTPS1	Membrane-bound transcription factor site-1 protease	0.981	landscape →
Q5WN23	—	0.980	Q5WN23 →
Q6NZ07	—	0.980	Q6NZ07 →
Q08919	—	0.980	Q08919 →
Q8GUM5	—	0.979	Q8GUM5 →
Q99ML5	—	0.979	Q99ML5 →
P91406	—	0.978	P91406 →
Q61847	—	0.978	Q61847 →
Q91687	—	0.978	Q91687 →
Q6UPR8	—	0.978	Q6UPR8 →
ERMP1	Endoplasmic reticulum metallopeptidase 1	0.978	landscape →
Q08693	—	0.978	Q08693 →